Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice.

Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice.

BACKGROUND: Hormone-sensitive lipase (HSL) is expressed predominantly in adipose tissue, where it plays an important role in catecholamine-stimulated hydrolysis of stored lipids, thus mobilizing fatty acids. HSL exhibits broad substrate specificity and besides acylglycerides it hydrolyzes cholestery...

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Bibliographic Details
Main Authors:	Céline Fernandez, Kai Schuhmann, Ronny Herzog, Barbara Fielding, Keith Frayn, Andrej Shevchenko, Peter James, Cecilia Holm, Kristoffer Ström
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3126817?pdf=render

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