Food-borne norovirus-outbreak at a military base, Germany, 2009
<p>Abstract</p> <p>Background</p> <p>Norovirus is often transmitted from person-to-person. Transmission may also be food-borne, but only few norovirus outbreak investigations have identified food items as likely vehicles of norovirus transmission through an analytical e...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-02-01
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| Series: | BMC Infectious Diseases |
| Online Access: | http://www.biomedcentral.com/1471-2334/10/30 |
| _version_ | 1811293395695435776 |
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| author | Hoehne Marina Gatzer Renate Frank Christina Ellerbroek Lüppo Diedrich Sabine Nielsen Stine Scherer Kathrin Wadl Maria Johne Reimar Klein Günter Koch Judith Schulenburg Jörg Thielbein Uta Stark Klaus Bernard Helen |
| author_facet | Hoehne Marina Gatzer Renate Frank Christina Ellerbroek Lüppo Diedrich Sabine Nielsen Stine Scherer Kathrin Wadl Maria Johne Reimar Klein Günter Koch Judith Schulenburg Jörg Thielbein Uta Stark Klaus Bernard Helen |
| author_sort | Hoehne Marina |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Norovirus is often transmitted from person-to-person. Transmission may also be food-borne, but only few norovirus outbreak investigations have identified food items as likely vehicles of norovirus transmission through an analytical epidemiological study.</p> <p>During 7-9 January, 2009, 36 persons at a military base in Germany fell ill with acute gastroenteritis. Food from the military base's canteen was suspected as vehicle of infection, norovirus as the pathogen causing the illnesses. An investigation was initiated to describe the outbreak's extent, to verify the pathogen, and to identify modes of transmission and source of infection to prevent further cases.</p> <p>Methods</p> <p>For descriptive analysis, ill persons were defined as members of the military base with acute onset of diarrhoea or vomiting between 24 December 2008, and 3 February 2009, without detection of a pathogen other than norovirus in stools. We conducted a retrospective cohort study within the headquarters company. Cases were military base members with onset of diarrhoea or vomiting during 5-9 January. We collected information on demographics, food items eaten at the canteen and contact to ill persons or vomit, using a self-administered questionnaire. We compared attack rates (AR) in exposed and unexposed persons, using bivariable and multivariable logistic regression modelling. Stool specimens of ill persons and canteen employees, canteen food served during 5-7 January and environmental swabs were investigated by laboratory analysis.</p> <p>Results</p> <p>Overall, 101/815 (AR 12.4%) persons fell ill between 24 December 2008 and 3 February 2009. None were canteen employees. Most persons (n = 49) had disease onset during 7-9 January. Ill persons were a median of 22 years old, 92.9% were male. The response for the cohort study was 178/274 (72.1%). Of 27 cases (AR 15.2%), 25 had eaten at the canteen and 21 had consumed salad. Salad consumption on 6 January (aOR: 8.1; 95%CI: 1.5-45.4) and 7 January (aOR: 15.7; 95%CI: 2.2-74.1) were independently associated with increased risk of disease.</p> <p>Norovirus was detected in 8/28 ill persons' and 4/25 canteen employees' stools, 6/55 environmental swabs and 0/33 food items. Sequences were identical in environmental and stool samples (subtype II.4 2006b), except for those of canteen employees. Control measures comprised cohort isolation of symptomatic persons, exclusion of norovirus-positive canteen employees from work and disinfection of the canteen's kitchen.</p> <p>Conclusions</p> <p>Our investigation indicated that consumption of norovirus-contaminated salad caused the peak of the outbreak on 7-9 January. Strict personal hygiene and proper disinfection of environmental surfaces remain crucial to prevent norovirus transmission.</p> |
| first_indexed | 2024-04-13T05:00:47Z |
| format | Article |
| id | doaj.art-94ae5a1eac93488a8a299a3ec8139ff9 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-04-13T05:00:47Z |
| publishDate | 2010-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-94ae5a1eac93488a8a299a3ec8139ff92022-12-22T03:01:21ZengBMCBMC Infectious Diseases1471-23342010-02-011013010.1186/1471-2334-10-30Food-borne norovirus-outbreak at a military base, Germany, 2009Hoehne MarinaGatzer RenateFrank ChristinaEllerbroek LüppoDiedrich SabineNielsen StineScherer KathrinWadl MariaJohne ReimarKlein GünterKoch JudithSchulenburg JörgThielbein UtaStark KlausBernard Helen<p>Abstract</p> <p>Background</p> <p>Norovirus is often transmitted from person-to-person. Transmission may also be food-borne, but only few norovirus outbreak investigations have identified food items as likely vehicles of norovirus transmission through an analytical epidemiological study.</p> <p>During 7-9 January, 2009, 36 persons at a military base in Germany fell ill with acute gastroenteritis. Food from the military base's canteen was suspected as vehicle of infection, norovirus as the pathogen causing the illnesses. An investigation was initiated to describe the outbreak's extent, to verify the pathogen, and to identify modes of transmission and source of infection to prevent further cases.</p> <p>Methods</p> <p>For descriptive analysis, ill persons were defined as members of the military base with acute onset of diarrhoea or vomiting between 24 December 2008, and 3 February 2009, without detection of a pathogen other than norovirus in stools. We conducted a retrospective cohort study within the headquarters company. Cases were military base members with onset of diarrhoea or vomiting during 5-9 January. We collected information on demographics, food items eaten at the canteen and contact to ill persons or vomit, using a self-administered questionnaire. We compared attack rates (AR) in exposed and unexposed persons, using bivariable and multivariable logistic regression modelling. Stool specimens of ill persons and canteen employees, canteen food served during 5-7 January and environmental swabs were investigated by laboratory analysis.</p> <p>Results</p> <p>Overall, 101/815 (AR 12.4%) persons fell ill between 24 December 2008 and 3 February 2009. None were canteen employees. Most persons (n = 49) had disease onset during 7-9 January. Ill persons were a median of 22 years old, 92.9% were male. The response for the cohort study was 178/274 (72.1%). Of 27 cases (AR 15.2%), 25 had eaten at the canteen and 21 had consumed salad. Salad consumption on 6 January (aOR: 8.1; 95%CI: 1.5-45.4) and 7 January (aOR: 15.7; 95%CI: 2.2-74.1) were independently associated with increased risk of disease.</p> <p>Norovirus was detected in 8/28 ill persons' and 4/25 canteen employees' stools, 6/55 environmental swabs and 0/33 food items. Sequences were identical in environmental and stool samples (subtype II.4 2006b), except for those of canteen employees. Control measures comprised cohort isolation of symptomatic persons, exclusion of norovirus-positive canteen employees from work and disinfection of the canteen's kitchen.</p> <p>Conclusions</p> <p>Our investigation indicated that consumption of norovirus-contaminated salad caused the peak of the outbreak on 7-9 January. Strict personal hygiene and proper disinfection of environmental surfaces remain crucial to prevent norovirus transmission.</p>http://www.biomedcentral.com/1471-2334/10/30 |
| spellingShingle | Hoehne Marina Gatzer Renate Frank Christina Ellerbroek Lüppo Diedrich Sabine Nielsen Stine Scherer Kathrin Wadl Maria Johne Reimar Klein Günter Koch Judith Schulenburg Jörg Thielbein Uta Stark Klaus Bernard Helen Food-borne norovirus-outbreak at a military base, Germany, 2009 BMC Infectious Diseases |
| title | Food-borne norovirus-outbreak at a military base, Germany, 2009 |
| title_full | Food-borne norovirus-outbreak at a military base, Germany, 2009 |
| title_fullStr | Food-borne norovirus-outbreak at a military base, Germany, 2009 |
| title_full_unstemmed | Food-borne norovirus-outbreak at a military base, Germany, 2009 |
| title_short | Food-borne norovirus-outbreak at a military base, Germany, 2009 |
| title_sort | food borne norovirus outbreak at a military base germany 2009 |
| url | http://www.biomedcentral.com/1471-2334/10/30 |
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