| Summary: | Shaobei injection is a softening and shrinking agent, which is applied to treat axillary osmidrosis and rarely causes adverse reactions. Panniculitis is a skin disease that involves the subcutaneous fat layer. In this article, one case of panniculitis secondary to Shaobei injection was reported. The 37-year-old female patient developed left-sided subcutaneous nodules complicated with pain at 8 d after Shaobei injection. Subsequently, subcutaneous fat liquefaction and necrosis occurred, which were recovered after incision and drainage. Pathological examination of subcutaneous tissues of the lesions displayed degeneration and necrosis of fibrous adipose tissues. The patient was diagnosed with panniculitis. This case prompts that although Shaobei injection rarely yields adverse reactions, it might lead to panniculitis. For patients developing panniculitis post-Shaobei injection, incision and drainage should be performed to promptly eliminate the lesions.
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