Regulation of Cortico-Thalamic JNK1/2 and ERK1/2 MAPKs and Apoptosis-Related Signaling Pathways in PDYN Gene-Deficient Mice Following Acute and Chronic Mild Stress

Regulation of Cortico-Thalamic JNK1/2 and ERK1/2 MAPKs and Apoptosis-Related Signaling Pathways in PDYN Gene-Deficient Mice Following Acute and Chronic Mild Stress

The crosstalk between the opioidergic system and mitogen-activated protein kinases (MAPKs) has a critical role in mediating stress-induced behaviors related to the pathophysiology of anxiety. The present study evaluated the basal status and stress-induced alterations of cortico-thalamic MAPKs and ot...

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Bibliographic Details
Main Authors: Fernando Yáñez-Gómez, Alfredo Ramos-Miguel, Jesús A. García-Sevilla, Jorge Manzanares, Teresa Femenía
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
prodynorphin
JNK
ERK
chronic mild stress
apoptosis
phosphorylation
Online Access:https://www.mdpi.com/1422-0067/24/3/2303

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