The bacterial lectin LecA from P. aeruginosa alters membrane organization by dispersing ordered domains

Abstract The dynamic reorganization of plasma membrane nanodomains (lipid rafts) plays a key role in host cell infection by human pathogens. Bacteria can induce the reorganization of lipid rafts as a result of the interactions between bacterial lectins and lipid raft glycosphingolipids (GSLs). Howev...

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Bibliographic Details
Main Authors: Taras Sych, Ramin Omidvar, Rafael Ostmann, Thomas Schubert, Annette Brandel, Ludovic Richert, Yves Mely, Josef Madl, Winfried Römer
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Communications Physics
Online Access:https://doi.org/10.1038/s42005-023-01272-3