Pediatric upper lip myopericytoma: a case report and comprehensive review
Abstract Background Myopericytoma is a rare spindle cell tumor of mesenchymal origin, typically benign, characterized by concentric proliferation of tumor cells around blood vessels within subcutaneous tissue. It primarily occurs in middle-aged adults and is often located in distal extremities, alth...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2024-04-01
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| Series: | BMC Oral Health |
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| Online Access: | https://doi.org/10.1186/s12903-024-04106-y |
| _version_ | 1827276914163712000 |
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| author | Bin Wei Gui Liu Kun Li Hongzhi Quan |
| author_facet | Bin Wei Gui Liu Kun Li Hongzhi Quan |
| author_sort | Bin Wei |
| collection | DOAJ |
| description | Abstract Background Myopericytoma is a rare spindle cell tumor of mesenchymal origin, typically benign, characterized by concentric proliferation of tumor cells around blood vessels within subcutaneous tissue. It primarily occurs in middle-aged adults and is often located in distal extremities, although cases have been reported in proximal extremities and head-neck regions. However, occurrences within the oral cavity are exceedingly rare. To date, literature reviews have identified only two cases in children under 10 years old and reported only five cases of myopericytoma occurring in the lip region. We provide a comprehensive review and analysis of all documented cases to better understand this condition. Case presentation A 7-year-old girl presented to oral and maxillofacial surgery with the discovery of a painless mass on the inner aspect of the upper lip. The diagnosis of myopericytoma was confirmed by histological examination (HE staining), alcian blue staining, and immunohistochemistry. Conclusions Following surgical excision, there were no signs of recurrence at a 3-month follow-up. The pathological diagnosis of myopericytoma is quite challenging, and immunohistochemical testing is necessary. |
| first_indexed | 2024-04-24T07:10:58Z |
| format | Article |
| id | doaj.art-94b6b32e0b024e5999f8d8de9df6901e |
| institution | Directory Open Access Journal |
| issn | 1472-6831 |
| language | English |
| last_indexed | 2024-04-24T07:10:58Z |
| publishDate | 2024-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj.art-94b6b32e0b024e5999f8d8de9df6901e2024-04-21T11:32:15ZengBMCBMC Oral Health1472-68312024-04-012411810.1186/s12903-024-04106-yPediatric upper lip myopericytoma: a case report and comprehensive reviewBin Wei0Gui Liu1Kun Li2Hongzhi Quan3Department of Oral and Maxillofacial Surgery, Xiangya Stomatological Hospital & School of Stomatology, Central South UniversityHunan Key Laboratory of Oral Health Research & Hunan 3D Printing Engineering Research Center of Oral Care & Hunan Clinical Research Center of Oral Major Diseases and Oral Health & Xiangya Stomatological Hospital, Xiangya School of Stomatology, Central South UniversityDepartment of Oral and Maxillofacial Surgery, Xiangya Stomatological Hospital & School of Stomatology, Central South UniversityDepartment of Oral and Maxillofacial Surgery, Xiangya Stomatological Hospital & School of Stomatology, Central South UniversityAbstract Background Myopericytoma is a rare spindle cell tumor of mesenchymal origin, typically benign, characterized by concentric proliferation of tumor cells around blood vessels within subcutaneous tissue. It primarily occurs in middle-aged adults and is often located in distal extremities, although cases have been reported in proximal extremities and head-neck regions. However, occurrences within the oral cavity are exceedingly rare. To date, literature reviews have identified only two cases in children under 10 years old and reported only five cases of myopericytoma occurring in the lip region. We provide a comprehensive review and analysis of all documented cases to better understand this condition. Case presentation A 7-year-old girl presented to oral and maxillofacial surgery with the discovery of a painless mass on the inner aspect of the upper lip. The diagnosis of myopericytoma was confirmed by histological examination (HE staining), alcian blue staining, and immunohistochemistry. Conclusions Following surgical excision, there were no signs of recurrence at a 3-month follow-up. The pathological diagnosis of myopericytoma is quite challenging, and immunohistochemical testing is necessary.https://doi.org/10.1186/s12903-024-04106-yMyopericytomaPediatric oral diseasesPathologyImmunohistochemical stainingHematoxylin and Eosin staining |
| spellingShingle | Bin Wei Gui Liu Kun Li Hongzhi Quan Pediatric upper lip myopericytoma: a case report and comprehensive review BMC Oral Health Myopericytoma Pediatric oral diseases Pathology Immunohistochemical staining Hematoxylin and Eosin staining |
| title | Pediatric upper lip myopericytoma: a case report and comprehensive review |
| title_full | Pediatric upper lip myopericytoma: a case report and comprehensive review |
| title_fullStr | Pediatric upper lip myopericytoma: a case report and comprehensive review |
| title_full_unstemmed | Pediatric upper lip myopericytoma: a case report and comprehensive review |
| title_short | Pediatric upper lip myopericytoma: a case report and comprehensive review |
| title_sort | pediatric upper lip myopericytoma a case report and comprehensive review |
| topic | Myopericytoma Pediatric oral diseases Pathology Immunohistochemical staining Hematoxylin and Eosin staining |
| url | https://doi.org/10.1186/s12903-024-04106-y |
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