Formulation and characterization of α-mangostin in chitosan nanoparticles coated by sodium alginate, sodium silicate, and polyethylene glycol

Formulation and characterization of α-mangostin in chitosan nanoparticles coated by sodium alginate, sodium silicate, and polyethylene glycol

Context: α-mangostin, one of the xanthone derivative compounds isolated from Garcinia mangostana L. peel extract, has an excellent anticancer efficacy. However, α-mangostin has a lack of site specificity, poor cells selectivity, and low aqueous solubility. Polymeric nanoparticles formulation can be...

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Bibliographic Details
Main Authors: Nasrul Wathoni, Agus Rusdin, Erma Febriani, Destiana Purnama, Wahnidar Daulay, Sundoro Y Azhary, Camellia Panatarani, I Made Joni, Ronny Lesmana, Keiichi Motoyama, Muchtaridi Muchtaridi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
alginate
chitosan
α-mangostin
polyethylene glycol
polymeric nanoparticle
silicate
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2019;volume=11;issue=8;spage=619;epage=627;aulast=Wathoni

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http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2019;volume=11;issue=8;spage=619;epage=627;aulast=Wathoni

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