What to Look Out for in a Newborn with Multiple Papulonodular Skin Lesions at Birth
Multiple papulonodular skin lesions at birth can indicate the presence of various benign and malignant disorders. Although the lesions’ clinical aspect (color and consistency, in particular) may steer the clinician towards one disorder or another (infantile myofibromatosis, xanthogranuloma, or metas...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-08-01
|
| Series: | Dermatopathology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2296-3529/8/3/43 |
| _version_ | 1829452833727971328 |
|---|---|
| author | Sylvie Fraitag Olivia Boccara |
| author_facet | Sylvie Fraitag Olivia Boccara |
| author_sort | Sylvie Fraitag |
| collection | DOAJ |
| description | Multiple papulonodular skin lesions at birth can indicate the presence of various benign and malignant disorders. Although the lesions’ clinical aspect (color and consistency, in particular) may steer the clinician towards one disorder or another (infantile myofibromatosis, xanthogranuloma, or metastatic neuroblastoma), the diagnosis can only be confirmed by the histopathologic assessment of a biopsy. In neonates, a rapid but accurate diagnosis is critical because skin lesions may be the first manifestation of a malignant disorder like leukemia cutis or metastatic neuroblastoma. Here, we review the various disorders that may manifest themselves as multiple skin lesions at birth. |
| first_indexed | 2024-03-10T07:46:37Z |
| format | Article |
| id | doaj.art-94ba783a3c944729a5a4894855d41f71 |
| institution | Directory Open Access Journal |
| issn | 2296-3529 |
| language | English |
| last_indexed | 2024-03-10T07:46:37Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Dermatopathology |
| spelling | doaj.art-94ba783a3c944729a5a4894855d41f712023-11-22T12:37:38ZengMDPI AGDermatopathology2296-35292021-08-018339041710.3390/dermatopathology8030043What to Look Out for in a Newborn with Multiple Papulonodular Skin Lesions at BirthSylvie Fraitag0Olivia Boccara1Department of Pathology, Necker-Enfants Malades Hospital, APHP, 75015 Paris, FranceDepartment of Dermatology, Necker-Enfants Malades Hospital, APHP, 75015 Paris, FranceMultiple papulonodular skin lesions at birth can indicate the presence of various benign and malignant disorders. Although the lesions’ clinical aspect (color and consistency, in particular) may steer the clinician towards one disorder or another (infantile myofibromatosis, xanthogranuloma, or metastatic neuroblastoma), the diagnosis can only be confirmed by the histopathologic assessment of a biopsy. In neonates, a rapid but accurate diagnosis is critical because skin lesions may be the first manifestation of a malignant disorder like leukemia cutis or metastatic neuroblastoma. Here, we review the various disorders that may manifest themselves as multiple skin lesions at birth.https://www.mdpi.com/2296-3529/8/3/43newbornblueberry muffin rashdermal erythropoiesisleukemia cutismetastatic neuroblastomametastatic rhabdomyosarcoma |
| spellingShingle | Sylvie Fraitag Olivia Boccara What to Look Out for in a Newborn with Multiple Papulonodular Skin Lesions at Birth Dermatopathology newborn blueberry muffin rash dermal erythropoiesis leukemia cutis metastatic neuroblastoma metastatic rhabdomyosarcoma |
| title | What to Look Out for in a Newborn with Multiple Papulonodular Skin Lesions at Birth |
| title_full | What to Look Out for in a Newborn with Multiple Papulonodular Skin Lesions at Birth |
| title_fullStr | What to Look Out for in a Newborn with Multiple Papulonodular Skin Lesions at Birth |
| title_full_unstemmed | What to Look Out for in a Newborn with Multiple Papulonodular Skin Lesions at Birth |
| title_short | What to Look Out for in a Newborn with Multiple Papulonodular Skin Lesions at Birth |
| title_sort | what to look out for in a newborn with multiple papulonodular skin lesions at birth |
| topic | newborn blueberry muffin rash dermal erythropoiesis leukemia cutis metastatic neuroblastoma metastatic rhabdomyosarcoma |
| url | https://www.mdpi.com/2296-3529/8/3/43 |
| work_keys_str_mv | AT sylviefraitag whattolookoutforinanewbornwithmultiplepapulonodularskinlesionsatbirth AT oliviaboccara whattolookoutforinanewbornwithmultiplepapulonodularskinlesionsatbirth |