A Markov chain Monte Carlo model of mechanical-feedback-driven progressive apical constrictions captures the fluctuating collective cell dynamics in the Drosophila embryo

A Markov chain Monte Carlo model of mechanical-feedback-driven progressive apical constrictions captures the fluctuating collective cell dynamics in the Drosophila embryo

Communication via mechanical stress feedback is believed to play an important role in the intercellular coordination of collective cellular movements. One such movement is ventral furrow formation (VFF) in the Drosophila melanogaster embryo. We previously introduced an active granular fluid (AGF) mo...

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Bibliographic Details
Main Authors: Guo–Jie J. Gao, Michael C. Holcomb, Jeffrey H. Thomas, Jerzy Blawzdziewicz
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Physics
Subjects:
Drosophila
embryo
morphogenesis
ventral furrow formation
cellular constrictions
mechanical feedback
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2022.971112/full

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