Novel High-Throughput Microwell Spectrophotometric Assay for One-Step Determination of Lorlatinib, a Novel Potent Drug for the Treatment of Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer

Novel High-Throughput Microwell Spectrophotometric Assay for One-Step Determination of Lorlatinib, a Novel Potent Drug for the Treatment of Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer

<i>Background and Objectives:</i> Lorlatinib (LOR) belongs to the third-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors. People who are diagnosed with ALK-positive metastatic and advanced non-small cell lung cancer (NSCLC) are eligible to get it as a first-line tre...

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Bibliographic Details
Main Authors: Abdullah M. Al-Hossaini, Ibrahim A. Darwish, Hany W. Darwish
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Medicina
Subjects:
2,3-dichloro-3,5-dicyano-1,4-benzoquinone
lorlatinib
non-small cell lung cancer
charge transfer complex
spectrophotometry
high throughput
Online Access:https://www.mdpi.com/1648-9144/59/4/756

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