Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan
Abstract Background: Peripheral neuropathy is a serious complication of diabetes, which has socioeconomic consequences as well as a reduced quality of life. Early neuropathic process recognition and management could alter its course and considerably reduce the associated morbidity and mortality. Thi...
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Format: | Article |
Language: | English |
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Knowledge E
2024-03-01
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Series: | Sudan Journal of Medical Sciences |
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Online Access: | https://doi.org/10.18502/1sjms.v19i1.15761 |
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author | MohamedAhmed M Ibnouf Khalid Sirelkhatim Nasir Elhaboob Arabi Mohamed MAM Ibnouf |
author_facet | MohamedAhmed M Ibnouf Khalid Sirelkhatim Nasir Elhaboob Arabi Mohamed MAM Ibnouf |
author_sort | MohamedAhmed M Ibnouf |
collection | DOAJ |
description | Abstract Background: Peripheral neuropathy is a serious complication of diabetes, which has socioeconomic consequences as well as a reduced quality of life. Early neuropathic process recognition and management could alter its course and considerably reduce the associated morbidity and mortality. This study determines the effect of long-term glycemic control on diabetic peripheral neuropathy in people with type 2 diabetes (T2DM). Methods: A hospital-based study was carried out at the National Centre of Neurosciences and Ibrahim Malik Hospital in Khartoum. All individuals who were older than 18 years and have had T2DM for less than 10 years were recruited. Using accepted techniques, the BMI, HbA1c level, and nerve conduction studies (NCS) were measured. Data were analyzed using the Statistical Package for Social Sciences (SPSS), version 25.0 software. P-value ≤ 0.05 was considered significant. Results: Of the 95 patients with T2DM, 52 were male patients. Our findings showed that as the duration of diabetes increased, the sensory velocity reduced from 64.07 ± 3.22 to 54.00 ± 5.34 and the motor nerve from 63.39 ± 2.38 to 53.87 ± 2.08 (P = 0.05, P = 0.003, respectively). Additionally, with increased duration of diabetes, a significant decrease was seen in both motor nerve amplitude from 8.79 ± 3.11 to 6.94 ± 1.84 (P = 0.05) and sensory nerve amplitude from 25.71 ± 5.70 to 19.51 ± 6.51 (P = 0.003). Also, all parameters of NCS (velocity and amplitude) decreased when Hb A1c was > 6 – sensory velocity from 63.96 ± 2.36 to 55.49 ± 2.43 (P = 0.03) and motor velocity from 63.00 ± 2.59 to 51.44 ± 1.66 (P = 0.02). And sensory amplitude decreased from 26.91 ± 1.26 to 20.85 ± 2.1 (P = 0.05), while motor amplitude decreased from 6.88 ± 3.55 to 6.61 ± 3.29 (P = 0.05). Additionally, there is a substantial (P = 0.05) correlation between sensory and motor amplitudes and the BMI. Conclusion: High BMI and poorly controlled (high HbA1c) long-term diabetes had a negative impact on all nerve conduction study parameters. |
first_indexed | 2024-04-24T14:23:49Z |
format | Article |
id | doaj.art-94c366d5a563470ea0065514bb40514b |
institution | Directory Open Access Journal |
issn | 1858-5051 |
language | English |
last_indexed | 2024-04-24T14:23:49Z |
publishDate | 2024-03-01 |
publisher | Knowledge E |
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series | Sudan Journal of Medical Sciences |
spelling | doaj.art-94c366d5a563470ea0065514bb40514b2024-04-03T05:55:54ZengKnowledge ESudan Journal of Medical Sciences1858-50512024-03-011911510.18502/1sjms.v19i1.157611sjms.v19i1.15761Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in SudanMohamedAhmed M Ibnouf0Khalid Sirelkhatim1Nasir Elhaboob Arabi2Mohamed MAM Ibnouf3 Department of Surgery, Faculty of Medicine and Health Sciences, Omdurman Islamic University Department of Urology, Head Department of Surgery, Faculty of Medicine and Health Sciences, Omdurman Islamic University Department of Surgery, Faculty of Medicine and Health Sciences, Omdurman Islamic University Department of Urology, Faculty of Medicine and Health Sciences, Omdurman Islamic University ORCID:Abstract Background: Peripheral neuropathy is a serious complication of diabetes, which has socioeconomic consequences as well as a reduced quality of life. Early neuropathic process recognition and management could alter its course and considerably reduce the associated morbidity and mortality. This study determines the effect of long-term glycemic control on diabetic peripheral neuropathy in people with type 2 diabetes (T2DM). Methods: A hospital-based study was carried out at the National Centre of Neurosciences and Ibrahim Malik Hospital in Khartoum. All individuals who were older than 18 years and have had T2DM for less than 10 years were recruited. Using accepted techniques, the BMI, HbA1c level, and nerve conduction studies (NCS) were measured. Data were analyzed using the Statistical Package for Social Sciences (SPSS), version 25.0 software. P-value ≤ 0.05 was considered significant. Results: Of the 95 patients with T2DM, 52 were male patients. Our findings showed that as the duration of diabetes increased, the sensory velocity reduced from 64.07 ± 3.22 to 54.00 ± 5.34 and the motor nerve from 63.39 ± 2.38 to 53.87 ± 2.08 (P = 0.05, P = 0.003, respectively). Additionally, with increased duration of diabetes, a significant decrease was seen in both motor nerve amplitude from 8.79 ± 3.11 to 6.94 ± 1.84 (P = 0.05) and sensory nerve amplitude from 25.71 ± 5.70 to 19.51 ± 6.51 (P = 0.003). Also, all parameters of NCS (velocity and amplitude) decreased when Hb A1c was > 6 – sensory velocity from 63.96 ± 2.36 to 55.49 ± 2.43 (P = 0.03) and motor velocity from 63.00 ± 2.59 to 51.44 ± 1.66 (P = 0.02). And sensory amplitude decreased from 26.91 ± 1.26 to 20.85 ± 2.1 (P = 0.05), while motor amplitude decreased from 6.88 ± 3.55 to 6.61 ± 3.29 (P = 0.05). Additionally, there is a substantial (P = 0.05) correlation between sensory and motor amplitudes and the BMI. Conclusion: High BMI and poorly controlled (high HbA1c) long-term diabetes had a negative impact on all nerve conduction study parameters.https://doi.org/10.18502/1sjms.v19i1.15761diabetes mellitus, peripheral nerve neuropathy, body mass index |
spellingShingle | MohamedAhmed M Ibnouf Khalid Sirelkhatim Nasir Elhaboob Arabi Mohamed MAM Ibnouf Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan Sudan Journal of Medical Sciences diabetes mellitus, peripheral nerve neuropathy, body mass index |
title | Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan |
title_full | Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan |
title_fullStr | Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan |
title_full_unstemmed | Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan |
title_short | Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan |
title_sort | commitment toward accreditation of medical schools during natural disasters and war in sudan |
topic | diabetes mellitus, peripheral nerve neuropathy, body mass index |
url | https://doi.org/10.18502/1sjms.v19i1.15761 |
work_keys_str_mv | AT mohamedahmedmibnouf commitmenttowardaccreditationofmedicalschoolsduringnaturaldisastersandwarinsudan AT khalidsirelkhatim commitmenttowardaccreditationofmedicalschoolsduringnaturaldisastersandwarinsudan AT nasirelhaboobarabi commitmenttowardaccreditationofmedicalschoolsduringnaturaldisastersandwarinsudan AT mohamedmamibnouf commitmenttowardaccreditationofmedicalschoolsduringnaturaldisastersandwarinsudan |