Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan

Abstract Background: Peripheral neuropathy is a serious complication of diabetes, which has socioeconomic consequences as well as a reduced quality of life. Early neuropathic process recognition and management could alter its course and considerably reduce the associated morbidity and mortality. Thi...

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Main Authors: MohamedAhmed M Ibnouf, Khalid Sirelkhatim, Nasir Elhaboob Arabi, Mohamed MAM Ibnouf
Format: Article
Language:English
Published: Knowledge E 2024-03-01
Series:Sudan Journal of Medical Sciences
Subjects:
Online Access:https://doi.org/10.18502/1sjms.v19i1.15761
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author MohamedAhmed M Ibnouf
Khalid Sirelkhatim
Nasir Elhaboob Arabi
Mohamed MAM Ibnouf
author_facet MohamedAhmed M Ibnouf
Khalid Sirelkhatim
Nasir Elhaboob Arabi
Mohamed MAM Ibnouf
author_sort MohamedAhmed M Ibnouf
collection DOAJ
description Abstract Background: Peripheral neuropathy is a serious complication of diabetes, which has socioeconomic consequences as well as a reduced quality of life. Early neuropathic process recognition and management could alter its course and considerably reduce the associated morbidity and mortality. This study determines the effect of long-term glycemic control on diabetic peripheral neuropathy in people with type 2 diabetes (T2DM). Methods: A hospital-based study was carried out at the National Centre of Neurosciences and Ibrahim Malik Hospital in Khartoum. All individuals who were older than 18 years and have had T2DM for less than 10 years were recruited. Using accepted techniques, the BMI, HbA1c level, and nerve conduction studies (NCS) were measured. Data were analyzed using the Statistical Package for Social Sciences (SPSS), version 25.0 software. P-value ≤ 0.05 was considered significant. Results: Of the 95 patients with T2DM, 52 were male patients. Our findings showed that as the duration of diabetes increased, the sensory velocity reduced from 64.07 ± 3.22 to 54.00 ± 5.34 and the motor nerve from 63.39 ± 2.38 to 53.87 ± 2.08 (P = 0.05, P = 0.003, respectively). Additionally, with increased duration of diabetes, a significant decrease was seen in both motor nerve amplitude from 8.79 ± 3.11 to 6.94 ± 1.84 (P = 0.05) and sensory nerve amplitude from 25.71 ± 5.70 to 19.51 ± 6.51 (P = 0.003). Also, all parameters of NCS (velocity and amplitude) decreased when Hb A1c was > 6 – sensory velocity from 63.96 ± 2.36 to 55.49 ± 2.43 (P = 0.03) and motor velocity from 63.00 ± 2.59 to 51.44 ± 1.66 (P = 0.02). And sensory amplitude decreased from 26.91 ± 1.26 to 20.85 ± 2.1 (P = 0.05), while motor amplitude decreased from 6.88 ± 3.55 to 6.61 ± 3.29 (P = 0.05). Additionally, there is a substantial (P = 0.05) correlation between sensory and motor amplitudes and the BMI. Conclusion: High BMI and poorly controlled (high HbA1c) long-term diabetes had a negative impact on all nerve conduction study parameters.
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spelling doaj.art-94c366d5a563470ea0065514bb40514b2024-04-03T05:55:54ZengKnowledge ESudan Journal of Medical Sciences1858-50512024-03-011911510.18502/1sjms.v19i1.157611sjms.v19i1.15761Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in SudanMohamedAhmed M Ibnouf0Khalid Sirelkhatim1Nasir Elhaboob Arabi2Mohamed MAM Ibnouf3 Department of Surgery, Faculty of Medicine and Health Sciences, Omdurman Islamic University Department of Urology, Head Department of Surgery, Faculty of Medicine and Health Sciences, Omdurman Islamic University Department of Surgery, Faculty of Medicine and Health Sciences, Omdurman Islamic University Department of Urology, Faculty of Medicine and Health Sciences, Omdurman Islamic University ORCID:Abstract Background: Peripheral neuropathy is a serious complication of diabetes, which has socioeconomic consequences as well as a reduced quality of life. Early neuropathic process recognition and management could alter its course and considerably reduce the associated morbidity and mortality. This study determines the effect of long-term glycemic control on diabetic peripheral neuropathy in people with type 2 diabetes (T2DM). Methods: A hospital-based study was carried out at the National Centre of Neurosciences and Ibrahim Malik Hospital in Khartoum. All individuals who were older than 18 years and have had T2DM for less than 10 years were recruited. Using accepted techniques, the BMI, HbA1c level, and nerve conduction studies (NCS) were measured. Data were analyzed using the Statistical Package for Social Sciences (SPSS), version 25.0 software. P-value ≤ 0.05 was considered significant. Results: Of the 95 patients with T2DM, 52 were male patients. Our findings showed that as the duration of diabetes increased, the sensory velocity reduced from 64.07 ± 3.22 to 54.00 ± 5.34 and the motor nerve from 63.39 ± 2.38 to 53.87 ± 2.08 (P = 0.05, P = 0.003, respectively). Additionally, with increased duration of diabetes, a significant decrease was seen in both motor nerve amplitude from 8.79 ± 3.11 to 6.94 ± 1.84 (P = 0.05) and sensory nerve amplitude from 25.71 ± 5.70 to 19.51 ± 6.51 (P = 0.003). Also, all parameters of NCS (velocity and amplitude) decreased when Hb A1c was > 6 – sensory velocity from 63.96 ± 2.36 to 55.49 ± 2.43 (P = 0.03) and motor velocity from 63.00 ± 2.59 to 51.44 ± 1.66 (P = 0.02). And sensory amplitude decreased from 26.91 ± 1.26 to 20.85 ± 2.1 (P = 0.05), while motor amplitude decreased from 6.88 ± 3.55 to 6.61 ± 3.29 (P = 0.05). Additionally, there is a substantial (P = 0.05) correlation between sensory and motor amplitudes and the BMI. Conclusion: High BMI and poorly controlled (high HbA1c) long-term diabetes had a negative impact on all nerve conduction study parameters.https://doi.org/10.18502/1sjms.v19i1.15761diabetes mellitus, peripheral nerve neuropathy, body mass index
spellingShingle MohamedAhmed M Ibnouf
Khalid Sirelkhatim
Nasir Elhaboob Arabi
Mohamed MAM Ibnouf
Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan
Sudan Journal of Medical Sciences
diabetes mellitus, peripheral nerve neuropathy, body mass index
title Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan
title_full Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan
title_fullStr Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan
title_full_unstemmed Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan
title_short Commitment Toward Accreditation of Medical Schools During Natural Disasters and War in Sudan
title_sort commitment toward accreditation of medical schools during natural disasters and war in sudan
topic diabetes mellitus, peripheral nerve neuropathy, body mass index
url https://doi.org/10.18502/1sjms.v19i1.15761
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AT khalidsirelkhatim commitmenttowardaccreditationofmedicalschoolsduringnaturaldisastersandwarinsudan
AT nasirelhaboobarabi commitmenttowardaccreditationofmedicalschoolsduringnaturaldisastersandwarinsudan
AT mohamedmamibnouf commitmenttowardaccreditationofmedicalschoolsduringnaturaldisastersandwarinsudan