Characterization of a Novel Model of Lumbar Ligamentum Flavum Hypertrophy in Bipedal Standing Mice

Characterization of a Novel Model of Lumbar Ligamentum Flavum Hypertrophy in Bipedal Standing Mice

Objective To explore the main causes of hypertrophied ligamentum flavum (HLF) and the possibility of using bipedal standing mouse model to simulate the pathological changes in human HLF. Methods Thirty‐two 8‐week‐old C57BL/6 male mice were randomly assigned to the experimental group (n = 16) and con...

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Bibliographic Details
Main Authors: Zhen‐yu Zheng, Peng Li, Xiang Ao, Lei Qian, Yong‐xing Peng, Jun Chu, Tao Jiang, Zheng‐nan Lian, Zhong‐min Zhang, Liang Wang
Format: Article
Language:English
Published: Wiley 2021-12-01
Series:Orthopaedic Surgery
Subjects:
Aging
Finite element analysis
Hypertrophy of ligamentum flavum
Mechanical stress
Mouse model
Online Access:https://doi.org/10.1111/os.13156

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