TRAIL/Apo-2L: Mechanisms and Clinical Applications in Cancer
TNF-related apoptosis-inducing ligand (TRAIL/APO2L) is a member of the TNF family that promotes apoptosis by binding to the transmembrane receptors TRAIL-R1 /DR4 and TRAIL-R2/DR5. Its cytotoxic activity is relatively selective to the human tumor cell lines without much effect on the normal cells. He...
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| Format: | Article |
| Language: | English |
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Elsevier
2001-01-01
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| Series: | Neoplasia: An International Journal for Oncology Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558601800099 |