Pinostrobin attenuates azoxymethane-induced colorectal cytotoxicity in rats through augmentation of apoptotic Bax/Bcl-2 proteins and antioxidants

Objectives: Pinostrobin (5-hydroxy-7-methoxyflavanone; PN) is a natural active ingredient with numerous biological activities extensively utilized in tumour chemotherapy. The present study investigates the chemo-preventive potentials of PN on azoxymethane-mediated colonic aberrant crypt foci in rats...

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Main Authors: Bassam Ali Abed Wahab, Nur Ain Salehen, Mahmood Ameen Abdulla, Ahmed A.j. Jabbar, Ibrahim Abdel Aziz Ibrahim, Ghassan Almaimani, Mustafa AbdulMonam Zainel, Ghazi A Bamagous, Riyad A Almaimani, Hussain A Almasmoum, Mazen M Ghaith, Wesam F Farrash, Yahya A Almutawif
Format: Article
Language:English
Published: SAGE Publishing 2023-12-01
Series:SAGE Open Medicine
Online Access:https://doi.org/10.1177/20503121231216585