Genetic polymorphisms in vitamin D receptor, vitamin D-binding protein, Toll-like receptor 2, nitric oxide synthase 2, and interferon-γ genes and its association with susceptibility to tuberculosis

Genetic polymorphisms in vitamin D receptor, vitamin D-binding protein, Toll-like receptor 2, nitric oxide synthase 2, and interferon-γ genes and its association with susceptibility to tuberculosis

Mycobacterium tuberculosis kills more people than any other single pathogen, with an estimated one-third of the world's population being infected. Among those infected, only 10% will develop the disease. There are several demonstrations that susceptibility to tuberculosis is linked to host gene...

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Bibliographic Details
Main Authors: A.C.C.S. Leandro, M.A. Rocha, C.S.A. Cardoso, M.G. Bonecini-Almeida
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2009-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Tuberculosis
Vitamin D
Vitamin D-binding protein
Toll-like receptor
Nitric oxide synthase 2
IFN-γ
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000400002

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