The Key Role of Purine Metabolism in the Folate-Dependent Phenotype of Autism Spectrum Disorders: An In Silico Analysis

The Key Role of Purine Metabolism in the Folate-Dependent Phenotype of Autism Spectrum Disorders: An In Silico Analysis

Folate deficiency in the critical developmental period has been repeatedly associated with an increased risk of Autism spectrum disorders (ASD), but the key pathophysiological mechanism has not yet been identified. In this work, we focused on identifying genes whose defect has similar consequences t...

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Bibliographic Details
Main Authors: Jan Geryk, Daniel Krsička, Markéta Vlčková, Markéta Havlovicová, Milan Macek, Radka Kremlíková Pourová
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Metabolites
Subjects:
autism
ASD
folate
blocked metabolite
purine
<i>ADSL</i>
Online Access:https://www.mdpi.com/2218-1989/10/5/184

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