Diagnosis and Treatment of Hypopituitarism
Hypopituitarism is a chronic endocrine illness that caused by varied etiologies. Clinical manifestations of hypopituitarism are variable, often insidious in onset and dependent on the degree and severity of hormone deficiency. However, it is associated with increased mortality and morbidity. Therefo...
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| Format: | Article |
| Language: | English |
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Korean Endocrine Society
2015-12-01
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| Series: | Endocrinology and Metabolism |
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| Online Access: | http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-30-443.pdf |
| _version_ | 1818367331649191936 |
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| author | Seong Yeon Kim |
| author_facet | Seong Yeon Kim |
| author_sort | Seong Yeon Kim |
| collection | DOAJ |
| description | Hypopituitarism is a chronic endocrine illness that caused by varied etiologies. Clinical manifestations of hypopituitarism are variable, often insidious in onset and dependent on the degree and severity of hormone deficiency. However, it is associated with increased mortality and morbidity. Therefore, early diagnosis and prompt treatment is necessary. Hypopituitarism can be easily diagnosed by measuring basal pituitary and target hormone levels except growth hormone (GH) and adrenocorticotropic hormone (ACTH) deficiency. Dynamic stimulation tests are indicated in equivocal basal hormone levels and GH/ACTH deficiency. Knowledge of the use and limitations of these stimulation tests is mandatory for proper interpretation. It is necessary for physicians to inform their patients that they may require lifetime treatment. Hormone replacement therapy should be individualized according to the specific needs of each patient, taking into account possible interactions. Long-term endocrinological follow-up of hypopituitary patients is important to monitor hormonal replacement regimes and avoid under- or overtreatment. |
| first_indexed | 2024-12-13T22:50:21Z |
| format | Article |
| id | doaj.art-94d127e244ff4b368bf2162ea23fc3d8 |
| institution | Directory Open Access Journal |
| issn | 2093-596X 2093-5978 |
| language | English |
| last_indexed | 2024-12-13T22:50:21Z |
| publishDate | 2015-12-01 |
| publisher | Korean Endocrine Society |
| record_format | Article |
| series | Endocrinology and Metabolism |
| spelling | doaj.art-94d127e244ff4b368bf2162ea23fc3d82022-12-21T23:28:38ZengKorean Endocrine SocietyEndocrinology and Metabolism2093-596X2093-59782015-12-0130444345510.3803/EnM.2015.30.4.44320844Diagnosis and Treatment of HypopituitarismSeong Yeon KimHypopituitarism is a chronic endocrine illness that caused by varied etiologies. Clinical manifestations of hypopituitarism are variable, often insidious in onset and dependent on the degree and severity of hormone deficiency. However, it is associated with increased mortality and morbidity. Therefore, early diagnosis and prompt treatment is necessary. Hypopituitarism can be easily diagnosed by measuring basal pituitary and target hormone levels except growth hormone (GH) and adrenocorticotropic hormone (ACTH) deficiency. Dynamic stimulation tests are indicated in equivocal basal hormone levels and GH/ACTH deficiency. Knowledge of the use and limitations of these stimulation tests is mandatory for proper interpretation. It is necessary for physicians to inform their patients that they may require lifetime treatment. Hormone replacement therapy should be individualized according to the specific needs of each patient, taking into account possible interactions. Long-term endocrinological follow-up of hypopituitary patients is important to monitor hormonal replacement regimes and avoid under- or overtreatment.http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-30-443.pdfHypopituitarismAdrenocorticotropic hormone deficiencyThyrotropin deficiencyGonadotropin deficiencyGrowth hormone deficiencyAnti-diuretic hormone deficiency |
| spellingShingle | Seong Yeon Kim Diagnosis and Treatment of Hypopituitarism Endocrinology and Metabolism Hypopituitarism Adrenocorticotropic hormone deficiency Thyrotropin deficiency Gonadotropin deficiency Growth hormone deficiency Anti-diuretic hormone deficiency |
| title | Diagnosis and Treatment of Hypopituitarism |
| title_full | Diagnosis and Treatment of Hypopituitarism |
| title_fullStr | Diagnosis and Treatment of Hypopituitarism |
| title_full_unstemmed | Diagnosis and Treatment of Hypopituitarism |
| title_short | Diagnosis and Treatment of Hypopituitarism |
| title_sort | diagnosis and treatment of hypopituitarism |
| topic | Hypopituitarism Adrenocorticotropic hormone deficiency Thyrotropin deficiency Gonadotropin deficiency Growth hormone deficiency Anti-diuretic hormone deficiency |
| url | http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-30-443.pdf |
| work_keys_str_mv | AT seongyeonkim diagnosisandtreatmentofhypopituitarism |