scHiCTools: A computational toolbox for analyzing single-cell Hi-C data.
Single-cell Hi-C (scHi-C) sequencing technologies allow us to investigate three-dimensional chromatin organization at the single-cell level. However, we still need computational tools to deal with the sparsity of the contact maps from single cells and embed single cells in a lower-dimensional Euclid...
Main Authors: | Xinjun Li, Fan Feng, Hongxi Pu, Wai Yan Leung, Jie Liu |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-05-01
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Series: | PLoS Computational Biology |
Online Access: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1008978&type=printable |
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