The Various Oximetric Techniques Used for the Evaluation of Blood Oxygenation

Adequate oxygen delivery to a tissue depends on sufficient oxygen content in arterial blood and blood flow to the tissue. Oximetry is a technique for the assessment of blood oxygenation by measurements of light transmission through the blood, which is based on the different absorption spectra of oxy...

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Main Authors: Meir Nitzan, Itamar Nitzan, Yoel Arieli
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/20/17/4844
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author Meir Nitzan
Itamar Nitzan
Yoel Arieli
author_facet Meir Nitzan
Itamar Nitzan
Yoel Arieli
author_sort Meir Nitzan
collection DOAJ
description Adequate oxygen delivery to a tissue depends on sufficient oxygen content in arterial blood and blood flow to the tissue. Oximetry is a technique for the assessment of blood oxygenation by measurements of light transmission through the blood, which is based on the different absorption spectra of oxygenated and deoxygenated hemoglobin. Oxygen saturation in arterial blood provides information on the adequacy of respiration and is routinely measured in clinical settings, utilizing pulse oximetry. Oxygen saturation, in venous blood (SvO<sub>2</sub>) and in the entire blood in a tissue (StO<sub>2</sub>), is related to the blood supply to the tissue, and several oximetric techniques have been developed for their assessment. SvO<sub>2</sub> can be measured non-invasively in the fingers, making use of modified pulse oximetry, and in the retina, using the modified Beer–Lambert Law. StO<sub>2</sub> is measured in peripheral muscle and cerebral tissue by means of various modes of near infrared spectroscopy (NIRS), utilizing the relative transparency of infrared light in muscle and cerebral tissue. The primary problem of oximetry is the discrimination between absorption by hemoglobin and scattering by tissue elements in the attenuation measurement, and the various techniques developed for isolating the absorption effect are presented in the current review, with their limitations.
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spelling doaj.art-94d1e6ac84dc45f3b1d08951c69c0a532023-11-20T11:34:32ZengMDPI AGSensors1424-82202020-08-012017484410.3390/s20174844The Various Oximetric Techniques Used for the Evaluation of Blood OxygenationMeir Nitzan0Itamar Nitzan1Yoel Arieli2Department of Physics/Electro-Optics Engineering, Jerusalem College of Technology, 21 Havaad Haleumi St., Jerusalem 91160, IsraelMonash Newborn, Monash Children’s Hospital, Melbourne 3168, AustraliaDepartment of Physics/Electro-Optics Engineering, Jerusalem College of Technology, 21 Havaad Haleumi St., Jerusalem 91160, IsraelAdequate oxygen delivery to a tissue depends on sufficient oxygen content in arterial blood and blood flow to the tissue. Oximetry is a technique for the assessment of blood oxygenation by measurements of light transmission through the blood, which is based on the different absorption spectra of oxygenated and deoxygenated hemoglobin. Oxygen saturation in arterial blood provides information on the adequacy of respiration and is routinely measured in clinical settings, utilizing pulse oximetry. Oxygen saturation, in venous blood (SvO<sub>2</sub>) and in the entire blood in a tissue (StO<sub>2</sub>), is related to the blood supply to the tissue, and several oximetric techniques have been developed for their assessment. SvO<sub>2</sub> can be measured non-invasively in the fingers, making use of modified pulse oximetry, and in the retina, using the modified Beer–Lambert Law. StO<sub>2</sub> is measured in peripheral muscle and cerebral tissue by means of various modes of near infrared spectroscopy (NIRS), utilizing the relative transparency of infrared light in muscle and cerebral tissue. The primary problem of oximetry is the discrimination between absorption by hemoglobin and scattering by tissue elements in the attenuation measurement, and the various techniques developed for isolating the absorption effect are presented in the current review, with their limitations.https://www.mdpi.com/1424-8220/20/17/4844blood oxygenationoximetryoxygenated and deoxygenated hemoglobinlight absorption spectramodified Beer–Lambert Lawoxygen saturation
spellingShingle Meir Nitzan
Itamar Nitzan
Yoel Arieli
The Various Oximetric Techniques Used for the Evaluation of Blood Oxygenation
Sensors
blood oxygenation
oximetry
oxygenated and deoxygenated hemoglobin
light absorption spectra
modified Beer–Lambert Law
oxygen saturation
title The Various Oximetric Techniques Used for the Evaluation of Blood Oxygenation
title_full The Various Oximetric Techniques Used for the Evaluation of Blood Oxygenation
title_fullStr The Various Oximetric Techniques Used for the Evaluation of Blood Oxygenation
title_full_unstemmed The Various Oximetric Techniques Used for the Evaluation of Blood Oxygenation
title_short The Various Oximetric Techniques Used for the Evaluation of Blood Oxygenation
title_sort various oximetric techniques used for the evaluation of blood oxygenation
topic blood oxygenation
oximetry
oxygenated and deoxygenated hemoglobin
light absorption spectra
modified Beer–Lambert Law
oxygen saturation
url https://www.mdpi.com/1424-8220/20/17/4844
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