IntelliCage Automated Behavioral Phenotyping Reveals Behavior Deficits in the 3xTg-AD Mouse Model of Alzheimer’s Disease Associated With Brain Weight

IntelliCage Automated Behavioral Phenotyping Reveals Behavior Deficits in the 3xTg-AD Mouse Model of Alzheimer’s Disease Associated With Brain Weight

Transgenic rodent models of Alzheimer’s disease (AD) were designed to study mechanisms of pathogenesis and connect these mechanisms with cognitive decline. Measurements of cognition in rodents can be confounded, however, by human handling and interaction; the IntelliCage was created to circumvent th...

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Bibliographic Details
Main Authors: Wendy Winslow, Ian McDonough, Savannah Tallino, Annika Decker, Austin S. Vural, Ramon Velazquez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
IntelliCage
3xTg-AD
brain weight
cognition
amyloidosis
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.720214/full

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