Experience in the Adaptive Immunity Impacts Bone Homeostasis, Remodeling, and Healing

Experience in the Adaptive Immunity Impacts Bone Homeostasis, Remodeling, and Healing

Bone formation as well as bone healing capacity is known to be impaired in the elderly. Although bone formation is outpaced by bone resorption in aged individuals, we hereby present a novel path that considerably impacts bone formation and architecture: Bone formation is substantially reduced in age...

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Bibliographic Details
Main Authors: Christian H. Bucher, Claudia Schlundt, Dag Wulsten, F. Andrea Sass, Sebastian Wendler, Agnes Ellinghaus, Tobias Thiele, Ricarda Seemann, Bettina M. Willie, Hans-Dieter Volk, Georg N. Duda, Katharina Schmidt-Bleek
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
osteoimmunology
regeneration
bone healing
T cells
adaptive immunity
immune experience
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00797/full

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