Evaluating Organism-Wide Changes in the Metabolome and Microbiome following a Single Dose of Antibiotic

Evaluating Organism-Wide Changes in the Metabolome and Microbiome following a Single Dose of Antibiotic

ABSTRACT Antibiotics are a mainstay of modern medicine, but as they kill their target pathogen(s), they often affect the commensal microbiota. Antibiotic-induced microbiome dysbiosis is a growing research focus and health concern, often assessed via analysis of fecal samples. However, such analysis...

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Bibliographic Details
Main Authors: Alison Vrbanac, Kathryn A. Patras, Alan K. Jarmusch, Robert H. Mills, Samuel R. Shing, Robert A. Quinn, Fernando Vargas, David J. Gonzalez, Pieter C. Dorrestein, Rob Knight, Victor Nizet
Format: Article
Language:English
Published: American Society for Microbiology 2020-10-01
Series:mSystems
Subjects:
3D data visualization
antibiotics
mass spectrometry
metabolome
microbiome
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00340-20

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