The Protective Mechanism of Deuterated Linoleic Acid Involves the Activation of the Ca<sup>2+</sup> Signaling System of Astrocytes in Ischemia In Vitro

The Protective Mechanism of Deuterated Linoleic Acid Involves the Activation of the Ca<sup>2+</sup> Signaling System of Astrocytes in Ischemia In Vitro

Ischemia-like (oxygen-glucose deprivation, OGD) conditions followed by reoxygenation (OGD/R) cause massive death of cerebral cortex cells in culture as a result of the induction of necrosis and apoptosis. Cell death occurs as a result of an OGD-induced increase in Ca<sup>2+</sup> ions in...

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Bibliographic Details
Main Authors: Egor A. Turovsky, Elena G. Varlamova, Sergey V. Gudkov, Egor Y. Plotnikov
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
oxygen-glucose deprivation
cell death
cortex
astrocyte
cell protection
signaling
Online Access:https://www.mdpi.com/1422-0067/22/24/13216

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