Precision health in Alzheimer disease: Risk assessment‐based strategies
Abstract Alzheimer disease (AD) is a chronic neurodegenerative condition that affects an individual's cognitive function over an extended period. Treatment and prevention for AD have long been sought after; however, no strategy has yet been successful, as individuals with cognitive impairment u...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-06-01
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| Series: | Precision Medical Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/prm2.12036 |
| _version_ | 1818863173767266304 |
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| author | Jihan Azar Mohamed Salama Saravana Babu Chidambaram Buthaina Al‐Balushi Musthafa Mohamed Essa M. Walid Qoronfleh |
| author_facet | Jihan Azar Mohamed Salama Saravana Babu Chidambaram Buthaina Al‐Balushi Musthafa Mohamed Essa M. Walid Qoronfleh |
| author_sort | Jihan Azar |
| collection | DOAJ |
| description | Abstract Alzheimer disease (AD) is a chronic neurodegenerative condition that affects an individual's cognitive function over an extended period. Treatment and prevention for AD have long been sought after; however, no strategy has yet been successful, as individuals with cognitive impairment usually present to the clinic when they have reached an advanced stage of the disease. The disease is progressive and multifactorial in its pathogenesis. Precision medicine (PM) is the new era of medicine comprising a holistic approach in dealing with diseases. With scientific innovations, PM has improved our disease knowledge, altered diagnoses and therapy approaches resulting in a more precise, predictive, preventative and personalized patient care. PM in AD focuses, among other things, on stratifying individuals according to their risk factors of developing the disease and applying preventative strategies and personalized treatment approaches for a better outcome. In this mini‐review, we have focused on a few modifiable and non‐modifiable risk factors and presented recommendations for future consideration to implement. |
| first_indexed | 2024-12-19T10:11:33Z |
| format | Article |
| id | doaj.art-94da07c050d14b23bdcb09eff53542ab |
| institution | Directory Open Access Journal |
| issn | 2642-2514 |
| language | English |
| last_indexed | 2024-12-19T10:11:33Z |
| publishDate | 2021-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Precision Medical Sciences |
| spelling | doaj.art-94da07c050d14b23bdcb09eff53542ab2022-12-21T20:26:21ZengWileyPrecision Medical Sciences2642-25142021-06-01102547010.1002/prm2.12036Precision health in Alzheimer disease: Risk assessment‐based strategiesJihan Azar0Mohamed Salama1Saravana Babu Chidambaram2Buthaina Al‐Balushi3Musthafa Mohamed Essa4M. Walid Qoronfleh5Institute of Global Health and Human Ecology (I‐GHHE) The American University in Cairo (AUC) Cairo EgyptInstitute of Global Health and Human Ecology (I‐GHHE) The American University in Cairo (AUC) Cairo EgyptDepartment of Pharmacology JSS College of Pharmacy, JSS Academy of Higher Education & Research Mysuru IndiaDepartment of Food Science and Nutrition CAMS, Sultan Qaboos University Muscat OmanDepartment of Food Science and Nutrition CAMS, Sultan Qaboos University Muscat OmanQ3CG Research Institute (QRI) Research & Policy Division Ypsilanti Michigan USAAbstract Alzheimer disease (AD) is a chronic neurodegenerative condition that affects an individual's cognitive function over an extended period. Treatment and prevention for AD have long been sought after; however, no strategy has yet been successful, as individuals with cognitive impairment usually present to the clinic when they have reached an advanced stage of the disease. The disease is progressive and multifactorial in its pathogenesis. Precision medicine (PM) is the new era of medicine comprising a holistic approach in dealing with diseases. With scientific innovations, PM has improved our disease knowledge, altered diagnoses and therapy approaches resulting in a more precise, predictive, preventative and personalized patient care. PM in AD focuses, among other things, on stratifying individuals according to their risk factors of developing the disease and applying preventative strategies and personalized treatment approaches for a better outcome. In this mini‐review, we have focused on a few modifiable and non‐modifiable risk factors and presented recommendations for future consideration to implement.https://doi.org/10.1002/prm2.12036Alzheimer diseasedementialifestyle medicinepersonalized healthcareprecision medicineprevention |
| spellingShingle | Jihan Azar Mohamed Salama Saravana Babu Chidambaram Buthaina Al‐Balushi Musthafa Mohamed Essa M. Walid Qoronfleh Precision health in Alzheimer disease: Risk assessment‐based strategies Precision Medical Sciences Alzheimer disease dementia lifestyle medicine personalized healthcare precision medicine prevention |
| title | Precision health in Alzheimer disease: Risk assessment‐based strategies |
| title_full | Precision health in Alzheimer disease: Risk assessment‐based strategies |
| title_fullStr | Precision health in Alzheimer disease: Risk assessment‐based strategies |
| title_full_unstemmed | Precision health in Alzheimer disease: Risk assessment‐based strategies |
| title_short | Precision health in Alzheimer disease: Risk assessment‐based strategies |
| title_sort | precision health in alzheimer disease risk assessment based strategies |
| topic | Alzheimer disease dementia lifestyle medicine personalized healthcare precision medicine prevention |
| url | https://doi.org/10.1002/prm2.12036 |
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