Astatine-211-Labeled Gold Nanoparticles for Targeted Alpha-Particle Therapy via Intravenous Injection

Astatine-211-Labeled Gold Nanoparticles for Targeted Alpha-Particle Therapy via Intravenous Injection

Alpha-particle radiotherapy has gained considerable attention owing to its potent anti-cancer effect. <sup>211</sup>At, with a relatively short half-life of 7.2 h, emits an alpha particle within a few cell diameters with high kinetic energy, which damages cancer cells with high biologica...

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Bibliographic Details
Main Authors: Xuhao Huang, Kazuko Kaneda-Nakashima, Yuichiro Kadonaga, Kazuya Kabayama, Atsushi Shimoyama, Kazuhiro Ooe, Hiroki Kato, Atsushi Toyoshima, Atsushi Shinohara, Hiromitsu Haba, Yang Wang, Koichi Fukase
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
astatine-211
gold nanoparticles
targeted alpha-particle therapy
cancer therapy
pancreatic cancer
intravenous administration
Online Access:https://www.mdpi.com/1999-4923/14/12/2705

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https://www.mdpi.com/1999-4923/14/12/2705

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