L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells
The L-arginine precursor, L-citrulline, re-couples endothelial nitric oxide synthase, increases nitric oxide production, and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs. L-arginine can induce arginase, which, in turn, may diminish nitric oxide production. Our major pur...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-04-01
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| Series: | Pulmonary Circulation |
| Online Access: | https://doi.org/10.1177/20458940211006289 |