mcr-1 and blaKPC-3 in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal

Escherichia coli Ec36 was recovered from a patient in Portugal after treatment with meropenem and colistin. Besides an IncF plasmid with Tn1441d-blaKPC-3, already reported in clinical strains in this country, E. coli Ec36 co-harbored an IncX4::mcr-1 gene. Results highlight emerging co-resistance to...

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Main Authors: Marta Tacão, Rafael dos Santos Tavares, Pedro Teixeira, Inês Roxo, Elmano Ramalheira, Sónia Ferreira, Isabel Henriques
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2017-08-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/23/8/17-0162_article
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author Marta Tacão
Rafael dos Santos Tavares
Pedro Teixeira
Inês Roxo
Elmano Ramalheira
Sónia Ferreira
Isabel Henriques
author_facet Marta Tacão
Rafael dos Santos Tavares
Pedro Teixeira
Inês Roxo
Elmano Ramalheira
Sónia Ferreira
Isabel Henriques
author_sort Marta Tacão
collection DOAJ
description Escherichia coli Ec36 was recovered from a patient in Portugal after treatment with meropenem and colistin. Besides an IncF plasmid with Tn1441d-blaKPC-3, already reported in clinical strains in this country, E. coli Ec36 co-harbored an IncX4::mcr-1 gene. Results highlight emerging co-resistance to carbapenems and polymyxins after therapy with drugs from both classes.
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spelling doaj.art-94e54fe79f3b4be38dc578dccc69aa642022-12-22T00:43:37ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592017-08-012381419142110.3201/eid2308.170162mcr-1 and blaKPC-3 in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, PortugalMarta TacãoRafael dos Santos TavaresPedro TeixeiraInês RoxoElmano RamalheiraSónia FerreiraIsabel HenriquesEscherichia coli Ec36 was recovered from a patient in Portugal after treatment with meropenem and colistin. Besides an IncF plasmid with Tn1441d-blaKPC-3, already reported in clinical strains in this country, E. coli Ec36 co-harbored an IncX4::mcr-1 gene. Results highlight emerging co-resistance to carbapenems and polymyxins after therapy with drugs from both classes.https://wwwnc.cdc.gov/eid/article/23/8/17-0162_articleGene, carbapenem, meropenem, colistin, polymixinfluconazolelinezolidco-resistanceantimicrobialantibacterial
spellingShingle Marta Tacão
Rafael dos Santos Tavares
Pedro Teixeira
Inês Roxo
Elmano Ramalheira
Sónia Ferreira
Isabel Henriques
mcr-1 and blaKPC-3 in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal
Emerging Infectious Diseases
Gene, carbapenem, meropenem, colistin, polymixin
fluconazole
linezolid
co-resistance
antimicrobial
antibacterial
title mcr-1 and blaKPC-3 in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal
title_full mcr-1 and blaKPC-3 in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal
title_fullStr mcr-1 and blaKPC-3 in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal
title_full_unstemmed mcr-1 and blaKPC-3 in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal
title_short mcr-1 and blaKPC-3 in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal
title_sort mcr 1 and blakpc 3 in escherichia coli sequence type 744 after meropenem and colistin therapy portugal
topic Gene, carbapenem, meropenem, colistin, polymixin
fluconazole
linezolid
co-resistance
antimicrobial
antibacterial
url https://wwwnc.cdc.gov/eid/article/23/8/17-0162_article
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