Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium

Data in this article show radioligand uptake (to gamma counter and positron-emission-tomography) as well as polymerase chain reaction analyses of 18 kDa translocator protein (TSPO) quantification. We confirmed specificity of [18F]GE180 binding of rodent brain and myocardium by blocking experiments w...

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Bibliographic Details
Main Authors: Maximilian Deussing, Tanja Blume, Lena Vomacka, Christoph Mahler, Carola Focke, Andrei Todica, Marcus Unterrainer, Nathalie L. Albert, Simon Lindner, Barbara von Ungern-Sternberg, Karlheinz Baumann, Andreas Zwergal, Peter Bartenstein, Jochen Herms, Axel Rominger, Matthias Brendel
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340918304864
Description
Summary:Data in this article show radioligand uptake (to gamma counter and positron-emission-tomography) as well as polymerase chain reaction analyses of 18 kDa translocator protein (TSPO) quantification. We confirmed specificity of [18F]GE180 binding of rodent brain and myocardium by blocking experiments with prior application of non-radioactive GE180, using dynamic in vivo positron-emission-tomography and ex vivo gamma counter measurements. Expression of TSPO was compared between rodent brain and myocardium by quantitative polymerase chain reaction.
ISSN:2352-3409