Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium
Data in this article show radioligand uptake (to gamma counter and positron-emission-tomography) as well as polymerase chain reaction analyses of 18 kDa translocator protein (TSPO) quantification. We confirmed specificity of [18F]GE180 binding of rodent brain and myocardium by blocking experiments w...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-08-01
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| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340918304864 |
| _version_ | 1818161777209245696 |
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| author | Maximilian Deussing Tanja Blume Lena Vomacka Christoph Mahler Carola Focke Andrei Todica Marcus Unterrainer Nathalie L. Albert Simon Lindner Barbara von Ungern-Sternberg Karlheinz Baumann Andreas Zwergal Peter Bartenstein Jochen Herms Axel Rominger Matthias Brendel |
| author_facet | Maximilian Deussing Tanja Blume Lena Vomacka Christoph Mahler Carola Focke Andrei Todica Marcus Unterrainer Nathalie L. Albert Simon Lindner Barbara von Ungern-Sternberg Karlheinz Baumann Andreas Zwergal Peter Bartenstein Jochen Herms Axel Rominger Matthias Brendel |
| author_sort | Maximilian Deussing |
| collection | DOAJ |
| description | Data in this article show radioligand uptake (to gamma counter and positron-emission-tomography) as well as polymerase chain reaction analyses of 18 kDa translocator protein (TSPO) quantification. We confirmed specificity of [18F]GE180 binding of rodent brain and myocardium by blocking experiments with prior application of non-radioactive GE180, using dynamic in vivo positron-emission-tomography and ex vivo gamma counter measurements. Expression of TSPO was compared between rodent brain and myocardium by quantitative polymerase chain reaction. |
| first_indexed | 2024-12-11T16:23:09Z |
| format | Article |
| id | doaj.art-94efd4ec69854df9a2e9076084620ca9 |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-11T16:23:09Z |
| publishDate | 2018-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-94efd4ec69854df9a2e9076084620ca92022-12-22T00:58:47ZengElsevierData in Brief2352-34092018-08-0119331336Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardiumMaximilian Deussing0Tanja Blume1Lena Vomacka2Christoph Mahler3Carola Focke4Andrei Todica5Marcus Unterrainer6Nathalie L. Albert7Simon Lindner8Barbara von Ungern-Sternberg9Karlheinz Baumann10Andreas Zwergal11Peter Bartenstein12Jochen Herms13Axel Rominger14Matthias Brendel15Dept. of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, GermanyDept. of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany; Center for Neuropathology and Prion Research, Ludwig-Maximilians-Universität München, Munich, GermanyDept. of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, GermanyInst. of Clinical Neuroimmunology, Ludwig-Maximilians-Universität München, Munich, Germany; Biomedical Center (BMC), Ludwig-Maximilians-Universität München, Munich, GermanyDept. of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, GermanyDept. of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, GermanyDept. of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, GermanyDept. of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, GermanyDept. of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, GermanyDept. of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, GermanyRoche Pharma Research and Early Development, Neuroscience Discovery, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, SwitzerlandDept. of Neurology, Ludwig-Maximilians-Universität München, Munich, GermanyDept. of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, GermanyCenter for Neuropathology and Prion Research, Ludwig-Maximilians-Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; Department of Translational Brain Research, DZNE - German Center for Neurodegenerative Diseases, Munich, GermanyDept. of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, GermanyDept. of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany; Corresponding author.Data in this article show radioligand uptake (to gamma counter and positron-emission-tomography) as well as polymerase chain reaction analyses of 18 kDa translocator protein (TSPO) quantification. We confirmed specificity of [18F]GE180 binding of rodent brain and myocardium by blocking experiments with prior application of non-radioactive GE180, using dynamic in vivo positron-emission-tomography and ex vivo gamma counter measurements. Expression of TSPO was compared between rodent brain and myocardium by quantitative polymerase chain reaction.http://www.sciencedirect.com/science/article/pii/S2352340918304864 |
| spellingShingle | Maximilian Deussing Tanja Blume Lena Vomacka Christoph Mahler Carola Focke Andrei Todica Marcus Unterrainer Nathalie L. Albert Simon Lindner Barbara von Ungern-Sternberg Karlheinz Baumann Andreas Zwergal Peter Bartenstein Jochen Herms Axel Rominger Matthias Brendel Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium Data in Brief |
| title | Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium |
| title_full | Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium |
| title_fullStr | Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium |
| title_full_unstemmed | Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium |
| title_short | Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium |
| title_sort | data on specificity of 18f ge180 uptake for tspo expression in rodent brain and myocardium |
| url | http://www.sciencedirect.com/science/article/pii/S2352340918304864 |
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