In Vitro Studies of Chromone-Tetrazoles against Pathogenic Protozoa, Bacteria, and Fungi

In Vitro Studies of Chromone-Tetrazoles against Pathogenic Protozoa, Bacteria, and Fungi

In vitro studies to fourteen previously synthesized chromone-tetrazoles and four novel fluorine-containing analogs were conducted against pathogenic protozoan (Entamoeba histolytica), pathogenic bacteria (Pseudomonas aeruginosa, and Staphylococcus aureus), and human fungal pathogens (Sporothrix sche...

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Bibliographic Details
Main Authors: Pedro A. Cano, Alejandro Islas-Jácome, Ángeles Rangel-Serrano, Fernando Anaya-Velázquez, Felipe Padilla-Vaca, Elías Trujillo-Esquivel, Patricia Ponce-Noyola, Antonio Martínez-Richa, Rocío Gámez-Montaño
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Molecules
Subjects:
chromone-tetrazoles
Ugi-azide reaction
antimicrobial activity
pathogenic protozoa
pathogenic bacteria
pathogenic fungi
tropical diseases
Online Access:http://www.mdpi.com/1420-3049/20/7/12436
Description
Summary:In vitro studies to fourteen previously synthesized chromone-tetrazoles and four novel fluorine-containing analogs were conducted against pathogenic protozoan (Entamoeba histolytica), pathogenic bacteria (Pseudomonas aeruginosa, and Staphylococcus aureus), and human fungal pathogens (Sporothrix schenckii, Candida albicans, and Candida tropicalis), which have become in a serious health problem, mainly in tropical countries.
ISSN:1420-3049

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