A Novel Role for the Regulatory Nod-Like Receptor NLRP12 in Anti-Dengue Virus Response

A Novel Role for the Regulatory Nod-Like Receptor NLRP12 in Anti-Dengue Virus Response

Dengue Virus (DENV) infection can cause severe illness such as highly fatality dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Innate immune activation by Nod-like receptors (NLRs) is a critical part of host defense against viral infection. Here, we revealed a key mechanism of NLRP12...

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Bibliographic Details
Main Authors: Xingyu Li, Zhuo Dong, Yan Liu, Weifeng Song, Jieying Pu, Guanmin Jiang, Yongjian Wu, Lei Liu, Xi Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
DENV
NLRP12
PRDM1
HSP90
type I interferon
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.744880/full

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