Circ_0001825 promotes osteogenic differentiation in human-derived mesenchymal stem cells via miR-1270/SMAD5 axis

Circ_0001825 promotes osteogenic differentiation in human-derived mesenchymal stem cells via miR-1270/SMAD5 axis

Abstract Background The implication of deregulated circular RNAs in osteoporosis (OP) has gradually been proposed. Herein, we aimed to study the function and mechanism of circ_0001825 in OP using osteogenic-induced human-derived mesenchymal stem cells (hMSCs). Methods The content of genes and protei...

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Bibliographic Details
Main Authors: Changjun Zheng, Lingzhi Ding, Ziming Xiang, Mingxuan Feng, Fujiang Zhao, Zhaoxin Zhou, Chang She
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
circ_0001825
miR-1270
SMAD5
Osteoporosis
Osteogenic differentiation
Online Access:https://doi.org/10.1186/s13018-023-04133-5

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