脑小血管病脑白质损伤动物模型 Animal Models of Cerebral Small Vessel Disease with White Matter Lesion
【摘要】 脑小血管病是导致认知功能减退、步态情感障碍和痴呆的重要脑血管疾病,脑白质弥漫性损伤是该病的重要影像学特征。结合国内外近年来相关研究内容,本文对不同的脑小血管病白质损伤动物模型制作进行了系统性回顾,包括单一型动物模型如双侧颈总动脉狭窄模型、脑淀粉样血管病模型、Notch3转基因小鼠模型、自发性高血压大鼠模型、易卒中型肾血管性高血压大鼠模型,以及由两个或两个以上单一型动物模型组合而成的复合型动物模型等。 【Abstract】 In recent years, cerebral small vessel disease (CSVD) has been paid more and mo...
Main Author: | 董成亚,王伊龙,刘向荣 |
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Format: | Article |
Language: | zho |
Published: |
Editorial Department of Chinese Journal of Stroke
2019-05-01
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Series: | Zhongguo cuzhong zazhi |
Subjects: | |
Online Access: | http://www.chinastroke.org.cn/CN/article/openArticlePDF.jsp?id=2780 |
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