AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research

In this issue of PLOS Biology, Ibrahim and colleagues demonstrate how AlphaFold-multimer, an artificial intelligence–based structure prediction tool, can be used to identify sequence motifs binding to the ATG8 family of proteins central to autophagy. This Primer explores the implications of a new PL...

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Main Authors: Hallvard Lauritz Olsvik, Terje Johansen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-02-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907820/?tool=EBI
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author Hallvard Lauritz Olsvik
Terje Johansen
author_facet Hallvard Lauritz Olsvik
Terje Johansen
author_sort Hallvard Lauritz Olsvik
collection DOAJ
description In this issue of PLOS Biology, Ibrahim and colleagues demonstrate how AlphaFold-multimer, an artificial intelligence–based structure prediction tool, can be used to identify sequence motifs binding to the ATG8 family of proteins central to autophagy. This Primer explores the implications of a new PLOS Biology study which demonstrates how the AI-based structure prediction tool AlphaFold-multimer can be used to identify sequence motifs that bind to the ATG8 family of proteins central to autophagy.
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spelling doaj.art-94fcefab92714e8086b5cde023a9217b2023-02-12T05:30:27ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852023-02-01212AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy researchHallvard Lauritz OlsvikTerje JohansenIn this issue of PLOS Biology, Ibrahim and colleagues demonstrate how AlphaFold-multimer, an artificial intelligence–based structure prediction tool, can be used to identify sequence motifs binding to the ATG8 family of proteins central to autophagy. This Primer explores the implications of a new PLOS Biology study which demonstrates how the AI-based structure prediction tool AlphaFold-multimer can be used to identify sequence motifs that bind to the ATG8 family of proteins central to autophagy.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907820/?tool=EBI
spellingShingle Hallvard Lauritz Olsvik
Terje Johansen
AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research
PLoS Biology
title AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research
title_full AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research
title_fullStr AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research
title_full_unstemmed AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research
title_short AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research
title_sort alphafold multimer predicts atg8 protein binding motifs crucial for autophagy research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907820/?tool=EBI
work_keys_str_mv AT hallvardlauritzolsvik alphafoldmultimerpredictsatg8proteinbindingmotifscrucialforautophagyresearch
AT terjejohansen alphafoldmultimerpredictsatg8proteinbindingmotifscrucialforautophagyresearch