NLRP3 Inflammasome Promotes the Progression of Acute Myeloid Leukemia via IL-1β Pathway

NLRP3 Inflammasome Promotes the Progression of Acute Myeloid Leukemia via IL-1β Pathway

NLRP3 inflammasome has been reported to be associated with the pathogenesis of multiple solid tumors. However, the role of NLRP3 inflammasome in acute myeloid leukemia (AML) remains unclear. We showed that NLRP3 inflammasome is over-expressed and highly activated in AML bone marrow leukemia cells, w...

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Bibliographic Details
Main Authors: Chaoqin Zhong, Ruiqing Wang, Mingqiang Hua, Chen Zhang, Fengjiao Han, Miao Xu, Xinyu Yang, Guosheng Li, Xiang Hu, Tao Sun, Chunyan Ji, Daoxin Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
inflammasome
NLRP3
IL-1β
acute myeloid leukemia
progression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.661939/full

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