TNFα-Induced Oxidative Stress and Mitochondrial Dysfunction Alter Hypothalamic Neurogenesis and Promote Appetite Versus Satiety Neuropeptide Expression in Mice
Maternal obesity results in programmed offspring hyperphagia and obesity. The increased offspring food intake is due in part to the preferential differentiation of hypothalamic neuroprogenitor cells (NPCs) to orexigenic (AgRP) vs. anorexigenic (POMC) neurons. The altered neurogenesis may involve hyp...
Main Authors: | Mina Desai, Linsey Stiles, Adriana S. Torsoni, Marcio A. Torsoni, Orian S. Shirihai, Michael G. Ross |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-07-01
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Series: | Brain Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3425/12/7/900 |
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