Super-resolution ultrasound microvascular imaging: Is it ready for clinical use?
The field of super-resolution ultrasound microvascular imaging has been rapidly growing over the past decade. By leveraging contrast microbubbles as point targets for localization and tracking, super-resolution ultrasound pinpoints the location of microvessels and measures their blood flow velocity....
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| Format: | Article |
| Language: | English |
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Elsevier
2023-08-01
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| Series: | Zeitschrift für Medizinische Physik |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0939388923000430 |
| _version_ | 1797385294403600384 |
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| author | Pengfei Song Jonathan M. Rubin Matthew R. Lowerison |
| author_facet | Pengfei Song Jonathan M. Rubin Matthew R. Lowerison |
| author_sort | Pengfei Song |
| collection | DOAJ |
| description | The field of super-resolution ultrasound microvascular imaging has been rapidly growing over the past decade. By leveraging contrast microbubbles as point targets for localization and tracking, super-resolution ultrasound pinpoints the location of microvessels and measures their blood flow velocity. Super-resolution ultrasound is the first in vivo imaging modality that can image micron-scale vessels at a clinically relevant imaging depth without tissue destruction. These unique capabilities of super-resolution ultrasound provide structural (vessel morphology) and functional (vessel blood flow) assessments of tissue microvasculature on a global and local scale, which opens new doors for many enticing preclinical and clinical applications that benefit from microvascular biomarkers. The goal of this short review is to provide an update on recent advancements in super-resolution ultrasound imaging, with a focus on summarizing existing applications and discussing the prospects of translating super-resolution imaging to clinical practice and research. In this review, we also provide brief introductions of how super-resolution ultrasound works, how does it compare with other imaging modalities, and what are the tradeoffs and limitations for an audience who is not familiar with the technology. |
| first_indexed | 2024-03-08T21:52:04Z |
| format | Article |
| id | doaj.art-950c354182144191a21c04e4642e864a |
| institution | Directory Open Access Journal |
| issn | 0939-3889 |
| language | English |
| last_indexed | 2024-03-08T21:52:04Z |
| publishDate | 2023-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Zeitschrift für Medizinische Physik |
| spelling | doaj.art-950c354182144191a21c04e4642e864a2023-12-20T07:33:30ZengElsevierZeitschrift für Medizinische Physik0939-38892023-08-01333309323Super-resolution ultrasound microvascular imaging: Is it ready for clinical use?Pengfei Song0Jonathan M. Rubin1Matthew R. Lowerison2Department of Electrical and Computer Engineering, University of Illinois Urbana-Champaign, United States; Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, United States; Department of Bioengineering, University of Illinois Urbana-Champaign, United States; Carle Illinois College of Medicine, University of Illinois Urbana-Champaign, United States; Corresponding author: Pengfei Song. Department of Electrical and Computer Engineering, University of Illinois Urbana-Champaign, United States.Department of Radiology, University of Michigan, Ann Arbor, United StatesDepartment of Electrical and Computer Engineering, University of Illinois Urbana-Champaign, United States; Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, United StatesThe field of super-resolution ultrasound microvascular imaging has been rapidly growing over the past decade. By leveraging contrast microbubbles as point targets for localization and tracking, super-resolution ultrasound pinpoints the location of microvessels and measures their blood flow velocity. Super-resolution ultrasound is the first in vivo imaging modality that can image micron-scale vessels at a clinically relevant imaging depth without tissue destruction. These unique capabilities of super-resolution ultrasound provide structural (vessel morphology) and functional (vessel blood flow) assessments of tissue microvasculature on a global and local scale, which opens new doors for many enticing preclinical and clinical applications that benefit from microvascular biomarkers. The goal of this short review is to provide an update on recent advancements in super-resolution ultrasound imaging, with a focus on summarizing existing applications and discussing the prospects of translating super-resolution imaging to clinical practice and research. In this review, we also provide brief introductions of how super-resolution ultrasound works, how does it compare with other imaging modalities, and what are the tradeoffs and limitations for an audience who is not familiar with the technology.http://www.sciencedirect.com/science/article/pii/S0939388923000430Super-resolutionUltrasoundMicrovascular imagingUltrasound localization microscopy |
| spellingShingle | Pengfei Song Jonathan M. Rubin Matthew R. Lowerison Super-resolution ultrasound microvascular imaging: Is it ready for clinical use? Zeitschrift für Medizinische Physik Super-resolution Ultrasound Microvascular imaging Ultrasound localization microscopy |
| title | Super-resolution ultrasound microvascular imaging: Is it ready for clinical use? |
| title_full | Super-resolution ultrasound microvascular imaging: Is it ready for clinical use? |
| title_fullStr | Super-resolution ultrasound microvascular imaging: Is it ready for clinical use? |
| title_full_unstemmed | Super-resolution ultrasound microvascular imaging: Is it ready for clinical use? |
| title_short | Super-resolution ultrasound microvascular imaging: Is it ready for clinical use? |
| title_sort | super resolution ultrasound microvascular imaging is it ready for clinical use |
| topic | Super-resolution Ultrasound Microvascular imaging Ultrasound localization microscopy |
| url | http://www.sciencedirect.com/science/article/pii/S0939388923000430 |
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