Microwave ablation combined with cementoplasty under real-time temperature monitoring in the treatment of 82 patients with recurrent spinal metastases after radiotherapy
Abstract Background The spine is the most frequently affected part of the skeletal system to metastatic tumors. External radiotherapy is considered the first-line standard of care for these patients with spine metastases. Recurrent spinal metastases after radiotherapy cannot be treated with further...
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| Format: | Article |
| Language: | English |
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BMC
2022-11-01
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| Series: | BMC Musculoskeletal Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12891-022-05999-y |
| _version_ | 1828095711745409024 |
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| author | Baohu Wang Kaixian Zhang Xusheng Zhang Sen Yang Miaomiao Hu Peishun Li Wanying Yang Jing Fan Chao Xing Qianqian Yuan |
| author_facet | Baohu Wang Kaixian Zhang Xusheng Zhang Sen Yang Miaomiao Hu Peishun Li Wanying Yang Jing Fan Chao Xing Qianqian Yuan |
| author_sort | Baohu Wang |
| collection | DOAJ |
| description | Abstract Background The spine is the most frequently affected part of the skeletal system to metastatic tumors. External radiotherapy is considered the first-line standard of care for these patients with spine metastases. Recurrent spinal metastases after radiotherapy cannot be treated with further radiotherapy within a short period of time, making treatment difficult. We aimed to evaluate the effectiveness and safety of MWA combined with cementoplasty in the treatment of spinal metastases after radiotherapy under real-time temperature monitoring. Methods In this retrospective study, 82 patients with 115 spinal metastatic lesions were treated with MWA and cementoplasty under real-time temperature monitoring. Changes in visual analog scale (VAS) scores, daily morphine consumption, and Oswestry Disability Index (ODI) scores were noted. A paired Student’s t-test was used to assess these parameters. Complications during the procedure were graded using the CTCAE version 5.0. Results Technical success was attained in all patients. The mean VAS score was 6.3 ± 2.0 (range, 4–10) before operation, and remarkable decline was noted in one month (1.7 ± 1.0 [P < .001]), three months (1.4 ± 0.8 [P < .001]), and six months (1.3 ± 0.8 [P < .001]) after the operation. Significant reductions in daily morphine consumption and ODI scores were also observed (P < .05). Cement leakage was found in 27.8% (32/115) of lesions, with no obvious associated symptoms. Conclusion MWA combined with cementoplasty under real-time temperature monitoring is an effective and safe method for recurrent spinal metastases after radiotherapy. |
| first_indexed | 2024-04-11T07:17:57Z |
| format | Article |
| id | doaj.art-950c91a711c04edf92b3ed3da60b1347 |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-04-11T07:17:57Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-950c91a711c04edf92b3ed3da60b13472022-12-22T04:37:51ZengBMCBMC Musculoskeletal Disorders1471-24742022-11-012311710.1186/s12891-022-05999-yMicrowave ablation combined with cementoplasty under real-time temperature monitoring in the treatment of 82 patients with recurrent spinal metastases after radiotherapyBaohu Wang0Kaixian Zhang1Xusheng Zhang2Sen Yang3Miaomiao Hu4Peishun Li5Wanying Yang6Jing Fan7Chao Xing8Qianqian Yuan9Department of Oncology, Tengzhou Central People’s Hospital Affiliated to Jining Medical CollegeDepartment of Oncology, Tengzhou Central People’s Hospital Affiliated to Jining Medical CollegeDepartment of Oncology, Tengzhou Central People’s Hospital Affiliated to Jining Medical CollegeDepartment of Oncology, Tengzhou Central People’s Hospital Affiliated to Jining Medical CollegeDepartment of Oncology, Tengzhou Central People’s Hospital Affiliated to Jining Medical CollegeDepartment of Oncology, Tengzhou Central People’s Hospital Affiliated to Jining Medical CollegeDepartment of Oncology, Tengzhou Central People’s Hospital Affiliated to Jining Medical CollegeDepartment of Oncology, Tengzhou Central People’s Hospital Affiliated to Jining Medical CollegeDepartment of Oncology, Tengzhou Central People’s Hospital Affiliated to Jining Medical CollegeDepartment of Oncology, Tengzhou Central People’s Hospital Affiliated to Jining Medical CollegeAbstract Background The spine is the most frequently affected part of the skeletal system to metastatic tumors. External radiotherapy is considered the first-line standard of care for these patients with spine metastases. Recurrent spinal metastases after radiotherapy cannot be treated with further radiotherapy within a short period of time, making treatment difficult. We aimed to evaluate the effectiveness and safety of MWA combined with cementoplasty in the treatment of spinal metastases after radiotherapy under real-time temperature monitoring. Methods In this retrospective study, 82 patients with 115 spinal metastatic lesions were treated with MWA and cementoplasty under real-time temperature monitoring. Changes in visual analog scale (VAS) scores, daily morphine consumption, and Oswestry Disability Index (ODI) scores were noted. A paired Student’s t-test was used to assess these parameters. Complications during the procedure were graded using the CTCAE version 5.0. Results Technical success was attained in all patients. The mean VAS score was 6.3 ± 2.0 (range, 4–10) before operation, and remarkable decline was noted in one month (1.7 ± 1.0 [P < .001]), three months (1.4 ± 0.8 [P < .001]), and six months (1.3 ± 0.8 [P < .001]) after the operation. Significant reductions in daily morphine consumption and ODI scores were also observed (P < .05). Cement leakage was found in 27.8% (32/115) of lesions, with no obvious associated symptoms. Conclusion MWA combined with cementoplasty under real-time temperature monitoring is an effective and safe method for recurrent spinal metastases after radiotherapy.https://doi.org/10.1186/s12891-022-05999-yMicrowave ablationCementoplastyReal-time temperature monitoringRecurrent spinal metastases |
| spellingShingle | Baohu Wang Kaixian Zhang Xusheng Zhang Sen Yang Miaomiao Hu Peishun Li Wanying Yang Jing Fan Chao Xing Qianqian Yuan Microwave ablation combined with cementoplasty under real-time temperature monitoring in the treatment of 82 patients with recurrent spinal metastases after radiotherapy BMC Musculoskeletal Disorders Microwave ablation Cementoplasty Real-time temperature monitoring Recurrent spinal metastases |
| title | Microwave ablation combined with cementoplasty under real-time temperature monitoring in the treatment of 82 patients with recurrent spinal metastases after radiotherapy |
| title_full | Microwave ablation combined with cementoplasty under real-time temperature monitoring in the treatment of 82 patients with recurrent spinal metastases after radiotherapy |
| title_fullStr | Microwave ablation combined with cementoplasty under real-time temperature monitoring in the treatment of 82 patients with recurrent spinal metastases after radiotherapy |
| title_full_unstemmed | Microwave ablation combined with cementoplasty under real-time temperature monitoring in the treatment of 82 patients with recurrent spinal metastases after radiotherapy |
| title_short | Microwave ablation combined with cementoplasty under real-time temperature monitoring in the treatment of 82 patients with recurrent spinal metastases after radiotherapy |
| title_sort | microwave ablation combined with cementoplasty under real time temperature monitoring in the treatment of 82 patients with recurrent spinal metastases after radiotherapy |
| topic | Microwave ablation Cementoplasty Real-time temperature monitoring Recurrent spinal metastases |
| url | https://doi.org/10.1186/s12891-022-05999-y |
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