Malnutrition Is Associated with Diabetic Retinopathy in Patients with Type 2 Diabetes
Background. The relationship between malnutrition and diabetic retinopathy (DR) is still unclear. The purpose of this study is to investigate the relationship between malnutrition and DR in type 2 diabetic patients. Methods. A cross-sectional study was conducted on 612 patients with type 2 diabetes...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2023-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2023/1613727 |
| _version_ | 1797454708763262976 |
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| author | Wen Wei Ruiyu Lin Shihai Li Zheyuan Chen Qianqian Kang Fenyan Lv Wenying Zhong Hangju Chen Mei Tu |
| author_facet | Wen Wei Ruiyu Lin Shihai Li Zheyuan Chen Qianqian Kang Fenyan Lv Wenying Zhong Hangju Chen Mei Tu |
| author_sort | Wen Wei |
| collection | DOAJ |
| description | Background. The relationship between malnutrition and diabetic retinopathy (DR) is still unclear. The purpose of this study is to investigate the relationship between malnutrition and DR in type 2 diabetic patients. Methods. A cross-sectional study was conducted on 612 patients with type 2 diabetes mellitus. Four malnutrition assessment tools: Global Leadership Initiative on Malnutrition (GLIM) criteria, controlling nutritional status (CONUT), nutritional risk index (NRI), and prognostic nutritional index (PNI), were applied to assess the nutritional status of the study population. The association between malnutrition and DR was examined using multivariable logistic regression and ordered logistic regression. Results. The proportion of malnutrition varied from 10.0% to 34.3% in total patients and from 16.3% to 45.1% in DR patients across the assessment tools. DR patients were more likely to be malnourished than patients without DR. The adjusted odds ratios (aOR) and 95% confidence interval (CI) for DR of malnutrition defined by different tools were 1.86 (1.01-3.14) for GLIM criteria, 1.67 (1.04-2.70) for NRI, and 2.24 (1.07-4.69) for PNI. The aOR and 95% CI for the severity of DR of malnutrition defined by different tools were 1.99 (1.12-3.51) for GLIM criteria, 1.65 (1.06-2.58) for NRI, and 2.51 (1.31-4.79) for PNI. Conclusions. Malnutrition was common in DR patients, and it was closely linked to the presence and severity of DR. Diabetic patients with DR should undergo nutritional assessment and early treatment of malnutrition to prevent the onset or progression of DR. |
| first_indexed | 2024-03-09T15:41:58Z |
| format | Article |
| id | doaj.art-9516ad0df2664ff380bc8231f934bbe0 |
| institution | Directory Open Access Journal |
| issn | 2314-6753 |
| language | English |
| last_indexed | 2024-03-09T15:41:58Z |
| publishDate | 2023-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj.art-9516ad0df2664ff380bc8231f934bbe02023-11-25T00:00:03ZengHindawi LimitedJournal of Diabetes Research2314-67532023-01-01202310.1155/2023/1613727Malnutrition Is Associated with Diabetic Retinopathy in Patients with Type 2 DiabetesWen Wei0Ruiyu Lin1Shihai Li2Zheyuan Chen3Qianqian Kang4Fenyan Lv5Wenying Zhong6Hangju Chen7Mei Tu8Department of EndocrinologyDepartment of EndocrinologyDepartment of AnesthesiaDepartment of EndocrinologyDepartment of EndocrinologyDepartment of EndocrinologyDepartment of Physical ExaminationDepartment of EndocrinologyDepartment of EndocrinologyBackground. The relationship between malnutrition and diabetic retinopathy (DR) is still unclear. The purpose of this study is to investigate the relationship between malnutrition and DR in type 2 diabetic patients. Methods. A cross-sectional study was conducted on 612 patients with type 2 diabetes mellitus. Four malnutrition assessment tools: Global Leadership Initiative on Malnutrition (GLIM) criteria, controlling nutritional status (CONUT), nutritional risk index (NRI), and prognostic nutritional index (PNI), were applied to assess the nutritional status of the study population. The association between malnutrition and DR was examined using multivariable logistic regression and ordered logistic regression. Results. The proportion of malnutrition varied from 10.0% to 34.3% in total patients and from 16.3% to 45.1% in DR patients across the assessment tools. DR patients were more likely to be malnourished than patients without DR. The adjusted odds ratios (aOR) and 95% confidence interval (CI) for DR of malnutrition defined by different tools were 1.86 (1.01-3.14) for GLIM criteria, 1.67 (1.04-2.70) for NRI, and 2.24 (1.07-4.69) for PNI. The aOR and 95% CI for the severity of DR of malnutrition defined by different tools were 1.99 (1.12-3.51) for GLIM criteria, 1.65 (1.06-2.58) for NRI, and 2.51 (1.31-4.79) for PNI. Conclusions. Malnutrition was common in DR patients, and it was closely linked to the presence and severity of DR. Diabetic patients with DR should undergo nutritional assessment and early treatment of malnutrition to prevent the onset or progression of DR.http://dx.doi.org/10.1155/2023/1613727 |
| spellingShingle | Wen Wei Ruiyu Lin Shihai Li Zheyuan Chen Qianqian Kang Fenyan Lv Wenying Zhong Hangju Chen Mei Tu Malnutrition Is Associated with Diabetic Retinopathy in Patients with Type 2 Diabetes Journal of Diabetes Research |
| title | Malnutrition Is Associated with Diabetic Retinopathy in Patients with Type 2 Diabetes |
| title_full | Malnutrition Is Associated with Diabetic Retinopathy in Patients with Type 2 Diabetes |
| title_fullStr | Malnutrition Is Associated with Diabetic Retinopathy in Patients with Type 2 Diabetes |
| title_full_unstemmed | Malnutrition Is Associated with Diabetic Retinopathy in Patients with Type 2 Diabetes |
| title_short | Malnutrition Is Associated with Diabetic Retinopathy in Patients with Type 2 Diabetes |
| title_sort | malnutrition is associated with diabetic retinopathy in patients with type 2 diabetes |
| url | http://dx.doi.org/10.1155/2023/1613727 |
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