Implementing the 3T‐approach for cervical cancer screening in Cameroon: Preliminary results on program performance
Abstract Option recommended by World Health Organization (WHO) includes human papillomavirus (HPV) primary screening followed by visual inspection with acetic acid (VIA) triage. We implemented a program based on a 3T‐approach (Test‐Triage and Treat). Our objective was to verify the effectiveness of...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-10-01
|
| Series: | Cancer Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cam4.3355 |
| _version_ | 1797839407179366400 |
|---|---|
| author | Juliette Levy Marie dePreux Bruno Kenfack Jessica Sormani Rosa Catarino Eveline F. Tincho Chloé Frund Jovanny T. Fouogue Pierre Vassilakos Patrick Petignat |
| author_facet | Juliette Levy Marie dePreux Bruno Kenfack Jessica Sormani Rosa Catarino Eveline F. Tincho Chloé Frund Jovanny T. Fouogue Pierre Vassilakos Patrick Petignat |
| author_sort | Juliette Levy |
| collection | DOAJ |
| description | Abstract Option recommended by World Health Organization (WHO) includes human papillomavirus (HPV) primary screening followed by visual inspection with acetic acid (VIA) triage. We implemented a program based on a 3T‐approach (Test‐Triage and Treat). Our objective was to verify the effectiveness of the program by defining a set of performance indices. A sensitization campaign was performed in Dschang (Cameroon) and women aged 30‐49 years were invited to participate for screening based on the 3T‐approach. Participants performed HPV self‐sampling (Self‐HPV), analyzed with the point‐of‐care Xpert HPV assay followed by VIA/VILI triage and treatment if required. Key performance indicators (KPIs) for screening, diagnosis, treatment and follow‐up were defined, and achievable targets were described for which the approach is likely to be running optimally. A total of 840 women with a mean age of 39.4±5.9 years participated. The KPIs included (i) the screening rate (8.4% at 7 months, target =20% at 12 months), (ii) HPV positivity rate (19.8%, expected range 18‐25%), (iii) compliance to referral to VIA/VILI and complete test (100%, target >90%), (iv) compliance to referral to thermal ablation (100%, target >90%), (v) VIA/VILI positivity rate (50.6%, expected range 45‐55%), (vi) a single visit from diagnostic to treatment (79.8%, target >80%), (vii) compliance to follow‐up at 1 month (96.4%, target >80%) and (viii) at 6 months (70.6%, target >80%). Program performance based on the single‐visit 3T‐approach corresponded to defined targets and preliminary results support adequateness of KPIs for periodic monitoring. |
| first_indexed | 2024-04-09T15:57:28Z |
| format | Article |
| id | doaj.art-951706a0c54b4ae9a2f2115e9f087cf4 |
| institution | Directory Open Access Journal |
| issn | 2045-7634 |
| language | English |
| last_indexed | 2024-04-09T15:57:28Z |
| publishDate | 2020-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Medicine |
| spelling | doaj.art-951706a0c54b4ae9a2f2115e9f087cf42023-04-25T14:00:49ZengWileyCancer Medicine2045-76342020-10-019197293730010.1002/cam4.3355Implementing the 3T‐approach for cervical cancer screening in Cameroon: Preliminary results on program performanceJuliette Levy0Marie dePreux1Bruno Kenfack2Jessica Sormani3Rosa Catarino4Eveline F. Tincho5Chloé Frund6Jovanny T. Fouogue7Pierre Vassilakos8Patrick Petignat9Faculty of Medicine University of Geneva Geneva SwitzerlandFaculty of Medicine University of Geneva Geneva SwitzerlandFaculty of Medicine and Pharmaceutical Sciences University of DschangDschang District Hospital Dschang CameroonGynecology Division Department of Gynecology and Obstetrics University Hospitals of Geneva Geneva SwitzerlandGynecology Division Department of Gynecology and Obstetrics University Hospitals of Geneva Geneva SwitzerlandFaculty of Medicine and Biomedical Sciences Centre Hospitalier Universitaire (CHUY) Yaoundé CameroonGynecology Division Department of Gynecology and Obstetrics University Hospitals of Geneva Geneva SwitzerlandDepartment of Obstetrics and Gynecology Bafoussam Regional hospital Bafoussam CameroonGynecology Division Department of Gynecology and Obstetrics University Hospitals of Geneva Geneva SwitzerlandGynecology Division Department of Gynecology and Obstetrics University Hospitals of Geneva Geneva SwitzerlandAbstract Option recommended by World Health Organization (WHO) includes human papillomavirus (HPV) primary screening followed by visual inspection with acetic acid (VIA) triage. We implemented a program based on a 3T‐approach (Test‐Triage and Treat). Our objective was to verify the effectiveness of the program by defining a set of performance indices. A sensitization campaign was performed in Dschang (Cameroon) and women aged 30‐49 years were invited to participate for screening based on the 3T‐approach. Participants performed HPV self‐sampling (Self‐HPV), analyzed with the point‐of‐care Xpert HPV assay followed by VIA/VILI triage and treatment if required. Key performance indicators (KPIs) for screening, diagnosis, treatment and follow‐up were defined, and achievable targets were described for which the approach is likely to be running optimally. A total of 840 women with a mean age of 39.4±5.9 years participated. The KPIs included (i) the screening rate (8.4% at 7 months, target =20% at 12 months), (ii) HPV positivity rate (19.8%, expected range 18‐25%), (iii) compliance to referral to VIA/VILI and complete test (100%, target >90%), (iv) compliance to referral to thermal ablation (100%, target >90%), (v) VIA/VILI positivity rate (50.6%, expected range 45‐55%), (vi) a single visit from diagnostic to treatment (79.8%, target >80%), (vii) compliance to follow‐up at 1 month (96.4%, target >80%) and (viii) at 6 months (70.6%, target >80%). Program performance based on the single‐visit 3T‐approach corresponded to defined targets and preliminary results support adequateness of KPIs for periodic monitoring.https://doi.org/10.1002/cam4.3355cervical cancermanagementpreventionscreen‐and‐treatsub‐Saharan Africa |
| spellingShingle | Juliette Levy Marie dePreux Bruno Kenfack Jessica Sormani Rosa Catarino Eveline F. Tincho Chloé Frund Jovanny T. Fouogue Pierre Vassilakos Patrick Petignat Implementing the 3T‐approach for cervical cancer screening in Cameroon: Preliminary results on program performance Cancer Medicine cervical cancer management prevention screen‐and‐treat sub‐Saharan Africa |
| title | Implementing the 3T‐approach for cervical cancer screening in Cameroon: Preliminary results on program performance |
| title_full | Implementing the 3T‐approach for cervical cancer screening in Cameroon: Preliminary results on program performance |
| title_fullStr | Implementing the 3T‐approach for cervical cancer screening in Cameroon: Preliminary results on program performance |
| title_full_unstemmed | Implementing the 3T‐approach for cervical cancer screening in Cameroon: Preliminary results on program performance |
| title_short | Implementing the 3T‐approach for cervical cancer screening in Cameroon: Preliminary results on program performance |
| title_sort | implementing the 3t approach for cervical cancer screening in cameroon preliminary results on program performance |
| topic | cervical cancer management prevention screen‐and‐treat sub‐Saharan Africa |
| url | https://doi.org/10.1002/cam4.3355 |
| work_keys_str_mv | AT juliettelevy implementingthe3tapproachforcervicalcancerscreeningincameroonpreliminaryresultsonprogramperformance AT mariedepreux implementingthe3tapproachforcervicalcancerscreeningincameroonpreliminaryresultsonprogramperformance AT brunokenfack implementingthe3tapproachforcervicalcancerscreeningincameroonpreliminaryresultsonprogramperformance AT jessicasormani implementingthe3tapproachforcervicalcancerscreeningincameroonpreliminaryresultsonprogramperformance AT rosacatarino implementingthe3tapproachforcervicalcancerscreeningincameroonpreliminaryresultsonprogramperformance AT evelineftincho implementingthe3tapproachforcervicalcancerscreeningincameroonpreliminaryresultsonprogramperformance AT chloefrund implementingthe3tapproachforcervicalcancerscreeningincameroonpreliminaryresultsonprogramperformance AT jovannytfouogue implementingthe3tapproachforcervicalcancerscreeningincameroonpreliminaryresultsonprogramperformance AT pierrevassilakos implementingthe3tapproachforcervicalcancerscreeningincameroonpreliminaryresultsonprogramperformance AT patrickpetignat implementingthe3tapproachforcervicalcancerscreeningincameroonpreliminaryresultsonprogramperformance |