Breast manifestation of extramedullary myeloid sarcoma: A case report
Extramedullary myeloid sarcoma (MS) of the breast is a rare disease, representing 0.12% of all diagnoses of acute myeloid leukemia. We review a case of a 27-year-old female who presented with a palpable right breast mass. She subsequently underwent a biopsy, which showed breast tissue with diffuse i...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043322007725 |
| _version_ | 1811235299871686656 |
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| author | Saba Naamo, MD Samar Naamo, MD Srawasti Sarker, MS Megan Vasconez, DO Monica Froicu, MD, PhD |
| author_facet | Saba Naamo, MD Samar Naamo, MD Srawasti Sarker, MS Megan Vasconez, DO Monica Froicu, MD, PhD |
| author_sort | Saba Naamo, MD |
| collection | DOAJ |
| description | Extramedullary myeloid sarcoma (MS) of the breast is a rare disease, representing 0.12% of all diagnoses of acute myeloid leukemia. We review a case of a 27-year-old female who presented with a palpable right breast mass. She subsequently underwent a biopsy, which showed breast tissue with diffuse infiltrate of blasts compatible with MS. A bone marrow biopsy was performed with no evidence of leukemia or lymphoma. Therefore, a second breast biopsy was obtained for additional testing and cytogenetics which demonstrated positive (t8;21)(q22;q22) translocation associated with acute myeloid leukemia. Patient was admitted for induction of chemotherapy, but she subsequently developed neutropenic colitis and C. diff colitis. Unfortunately, her condition quickly deteriorated, and she passed away shortly after. This report aims to describe the clinical, radiographic, and pathological features of a case of extramedullary MS involving the breast. |
| first_indexed | 2024-04-12T11:48:30Z |
| format | Article |
| id | doaj.art-9519a29f360d49eb9567f28d0191613b |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-04-12T11:48:30Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-9519a29f360d49eb9567f28d0191613b2022-12-22T03:34:16ZengElsevierRadiology Case Reports1930-04332022-12-01171246604665Breast manifestation of extramedullary myeloid sarcoma: A case reportSaba Naamo, MD0Samar Naamo, MD1Srawasti Sarker, MS2Megan Vasconez, DO3Monica Froicu, MD, PhD4Department of Radiology, Geisinger Medical Center, 100 N Academy Ave, Danville, PA 17821, USA; Corresponding author.Department of Radiology, Stony Brook Medicine, 101 Nicolls Rd level 4, Stony Brook, NY 11794, USAPhiladelphia College of Osteopathic Medicine, 4170 City Ave, Philadelphia, PA 19131, USADepartment of Pathology, Geisinger Medical Center, 100 N Academy Ave, Danville, PA 17821, USADepartment of Radiology, Geisinger Medical Center, 100 N Academy Ave, Danville, PA 17821, USAExtramedullary myeloid sarcoma (MS) of the breast is a rare disease, representing 0.12% of all diagnoses of acute myeloid leukemia. We review a case of a 27-year-old female who presented with a palpable right breast mass. She subsequently underwent a biopsy, which showed breast tissue with diffuse infiltrate of blasts compatible with MS. A bone marrow biopsy was performed with no evidence of leukemia or lymphoma. Therefore, a second breast biopsy was obtained for additional testing and cytogenetics which demonstrated positive (t8;21)(q22;q22) translocation associated with acute myeloid leukemia. Patient was admitted for induction of chemotherapy, but she subsequently developed neutropenic colitis and C. diff colitis. Unfortunately, her condition quickly deteriorated, and she passed away shortly after. This report aims to describe the clinical, radiographic, and pathological features of a case of extramedullary MS involving the breast.http://www.sciencedirect.com/science/article/pii/S1930043322007725ExtramedullaryMyeloid SarcomaAcute Myeloid LeukemiaBreast MassBreast CancerBreast Biopsy SET KEYWORDS |
| spellingShingle | Saba Naamo, MD Samar Naamo, MD Srawasti Sarker, MS Megan Vasconez, DO Monica Froicu, MD, PhD Breast manifestation of extramedullary myeloid sarcoma: A case report Radiology Case Reports Extramedullary Myeloid Sarcoma Acute Myeloid Leukemia Breast Mass Breast Cancer Breast Biopsy SET KEYWORDS |
| title | Breast manifestation of extramedullary myeloid sarcoma: A case report |
| title_full | Breast manifestation of extramedullary myeloid sarcoma: A case report |
| title_fullStr | Breast manifestation of extramedullary myeloid sarcoma: A case report |
| title_full_unstemmed | Breast manifestation of extramedullary myeloid sarcoma: A case report |
| title_short | Breast manifestation of extramedullary myeloid sarcoma: A case report |
| title_sort | breast manifestation of extramedullary myeloid sarcoma a case report |
| topic | Extramedullary Myeloid Sarcoma Acute Myeloid Leukemia Breast Mass Breast Cancer Breast Biopsy SET KEYWORDS |
| url | http://www.sciencedirect.com/science/article/pii/S1930043322007725 |
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