Impact of Body Composition and Physical Function on Quality of Life After Gastrectomy for Gastric Cancer
PurposePatients with gastric cancer after gastrectomy often suffer from a decline in their quality of life (QoL), but the relationship between body composition (BC) and physical function on QoL has rarely been studied. This study aims to evaluate and determine the changes in QoL after gastrectomy an...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-01-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2021.832351/full |
| _version_ | 1818744460214796288 |
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| author | Wen-Bin Wang Hao-Nan Song Dong-Dong Huang Xin Luo Hui-Yang Cai Jing-Yi Yan Wei-Zhe Chen Chun-Gen Xing Qian-Tong Dong Qian-Tong Dong Xiao-Lei Chen |
| author_facet | Wen-Bin Wang Hao-Nan Song Dong-Dong Huang Xin Luo Hui-Yang Cai Jing-Yi Yan Wei-Zhe Chen Chun-Gen Xing Qian-Tong Dong Qian-Tong Dong Xiao-Lei Chen |
| author_sort | Wen-Bin Wang |
| collection | DOAJ |
| description | PurposePatients with gastric cancer after gastrectomy often suffer from a decline in their quality of life (QoL), but the relationship between body composition (BC) and physical function on QoL has rarely been studied. This study aims to evaluate and determine the changes in QoL after gastrectomy and the impact of BC and physical function on QoL.MethodsA total of 311 gastric cancer patients completed EORTC QLQ-C30 and EORTC QLQ-STO22 questionnaires before and 1, 3, 6 months post-surgery. Data including BC, handgrip strength (HGS) and 6-m gait speed (GS) were collected prospectively. Multiple linear regression analysis was used to determine the correlation between QoL and BC, HGS and GS.ResultsPatients had significantly worse scores after surgery on most function and symptom scales (p < 0.001), but most of these scales recovered within 6 months after surgery. A higher subcutaneous fat area (SFA)was associated with increased symptom scores 1 month after surgery. A higher GS is associated with a better global health status symptom.ConclusionPatients suffer from a decline in their QoL after gastrectomy for gastric cancer. Intervention strategies aiming at reducing SFA and improving GS may improve the QoL in patients underwent gastrectomy for gastric cancer. |
| first_indexed | 2024-12-18T02:44:39Z |
| format | Article |
| id | doaj.art-951aa9bd8b1345aea3c7a0496719a949 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-12-18T02:44:39Z |
| publishDate | 2022-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-951aa9bd8b1345aea3c7a0496719a9492022-12-21T21:23:34ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2022-01-01810.3389/fsurg.2021.832351832351Impact of Body Composition and Physical Function on Quality of Life After Gastrectomy for Gastric CancerWen-Bin Wang0Hao-Nan Song1Dong-Dong Huang2Xin Luo3Hui-Yang Cai4Jing-Yi Yan5Wei-Zhe Chen6Chun-Gen Xing7Qian-Tong Dong8Qian-Tong Dong9Xiao-Lei Chen10Department of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of General Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, ChinaDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of General Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, ChinaDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaPurposePatients with gastric cancer after gastrectomy often suffer from a decline in their quality of life (QoL), but the relationship between body composition (BC) and physical function on QoL has rarely been studied. This study aims to evaluate and determine the changes in QoL after gastrectomy and the impact of BC and physical function on QoL.MethodsA total of 311 gastric cancer patients completed EORTC QLQ-C30 and EORTC QLQ-STO22 questionnaires before and 1, 3, 6 months post-surgery. Data including BC, handgrip strength (HGS) and 6-m gait speed (GS) were collected prospectively. Multiple linear regression analysis was used to determine the correlation between QoL and BC, HGS and GS.ResultsPatients had significantly worse scores after surgery on most function and symptom scales (p < 0.001), but most of these scales recovered within 6 months after surgery. A higher subcutaneous fat area (SFA)was associated with increased symptom scores 1 month after surgery. A higher GS is associated with a better global health status symptom.ConclusionPatients suffer from a decline in their QoL after gastrectomy for gastric cancer. Intervention strategies aiming at reducing SFA and improving GS may improve the QoL in patients underwent gastrectomy for gastric cancer.https://www.frontiersin.org/articles/10.3389/fsurg.2021.832351/fullhandgrip strength (HGS)gait speedsubcutaneous fat area (SFA)visceral fat area (VFA)skeletal muscle density (SMD) |
| spellingShingle | Wen-Bin Wang Hao-Nan Song Dong-Dong Huang Xin Luo Hui-Yang Cai Jing-Yi Yan Wei-Zhe Chen Chun-Gen Xing Qian-Tong Dong Qian-Tong Dong Xiao-Lei Chen Impact of Body Composition and Physical Function on Quality of Life After Gastrectomy for Gastric Cancer Frontiers in Surgery handgrip strength (HGS) gait speed subcutaneous fat area (SFA) visceral fat area (VFA) skeletal muscle density (SMD) |
| title | Impact of Body Composition and Physical Function on Quality of Life After Gastrectomy for Gastric Cancer |
| title_full | Impact of Body Composition and Physical Function on Quality of Life After Gastrectomy for Gastric Cancer |
| title_fullStr | Impact of Body Composition and Physical Function on Quality of Life After Gastrectomy for Gastric Cancer |
| title_full_unstemmed | Impact of Body Composition and Physical Function on Quality of Life After Gastrectomy for Gastric Cancer |
| title_short | Impact of Body Composition and Physical Function on Quality of Life After Gastrectomy for Gastric Cancer |
| title_sort | impact of body composition and physical function on quality of life after gastrectomy for gastric cancer |
| topic | handgrip strength (HGS) gait speed subcutaneous fat area (SFA) visceral fat area (VFA) skeletal muscle density (SMD) |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2021.832351/full |
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