G2/M arrest and mitotic slippage induced by fenbendazole in canine melanoma cells

G2/M arrest and mitotic slippage induced by fenbendazole in canine melanoma cells

Abstract Background The use of fenbendazole (FBZ) in terminal cancer patients has recently increased, as anthelminthic drugs, such as FBZ and benzimidazole, exhibit anti‐tubulin effects in tumour cells. Objectives The present study evaluated the in vitro anti‐cancer effects of FBZ in five canine mel...

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Bibliographic Details
Main Authors: Sehoon Kim, Shashini Kanchanamala Perera, Seo‐In Choi, Robert B. Rebhun, Kyoung‐won Seo
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Veterinary Medicine and Science
Subjects:
anti‐tumour effect
apoptosis
canine melanoma cell
fenbendazole
G2/M cell cycle arrest
mitotic slippage
Online Access:https://doi.org/10.1002/vms3.733

Internet

https://doi.org/10.1002/vms3.733

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