The Relationship between the Expression of GATA4 and GATA6 with the Clinical Characteristics and Prognosis of Resectable Pancreatic Adenocarcinoma

The Relationship between the Expression of GATA4 and GATA6 with the Clinical Characteristics and Prognosis of Resectable Pancreatic Adenocarcinoma

GATA4 and GATA6 are transcription factors involved in the differentiation and development of PDAC. GATA6 expression is related to the classic molecular subtype, while its absence is related to the basal-like molecular subtype. The aim was to determine the clinical utility of IHC determination of GAT...

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Bibliographic Details
Main Authors: Victoria Heredia-Soto, Laura Gutiérrez-Sainz, Ismael Ghanem, Laura Guerra, Elena Palacios, Marta de Uribe, Lucía Trilla-Fuertes, María de Miguel, Paloma Cejas, Laura Medina, José Miguel Calderón, David Viñal, Marta Mendiola, Jaime Feliu
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biomedicines
Subjects:
pancreatic ductal adenocarcinoma
GATA6
GATA4
prognostic
survival
carcinogenesis
Online Access:https://www.mdpi.com/2227-9059/11/2/252

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