Role of p53 in Anticancer Drug Treatment- and Radiation-Induced Injury in Normal Small Intestine

Role of p53 in Anticancer Drug Treatment- and Radiation-Induced Injury in Normal Small Intestine

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In the human gastrointestinal tract, the functional mucosa of the small intestine has the highest capacity for absorption of nutrients and rapid proliferation rates, making it vulnerable to chemoradiotherapy. Recent understanding of the protective role of p53-mediated cell cycle arrest in the small...

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Bibliographic Details
Main Author: Shi Jin
Format: Article
Language:English
Published: China Anti-Cancer Association 2012-03-01
Series:Cancer Biology & Medicine
Subjects:
chemotherapy
genes
p53
DNA damage
small intestine
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1/575

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