Tumor-neutrophil crosstalk promotes in vitro and in vivo glioblastoma progression

Tumor-neutrophil crosstalk promotes in vitro and in vivo glioblastoma progression

IntroductionThe tumor microenvironment (TME) of glioblastoma (GB) is characterized by an increased infiltration of immunosuppressive cells that attenuate the antitumor immune response. The participation of neutrophils in tumor progression is still controversial and a dual role in the TME has been pr...

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Main Authors: Dominique S. Rubenich, Priscila O. de Souza, Natalia Omizzollo, Mariana R. Aubin, Paulo J. Basso, Luisa M. Silva, Eloisa M. da Silva, Fernanda C. Teixeira, Gabriela F.S. Gentil, Jordana L. Domagalski, Maico T. Cunha, Kerolainy A. Gadelha, Leonardo F. Diel, Nicolly E. Gelsleichter, Aline S. Rubenich, Gabriela S. Lenz, Aline M. de Abreu, Giselle M. Kroeff, Ana H. Paz, Fernanda Visioli, Marcelo L. Lamers, Marcia R. Wink, Paulo V. Worm, Anelise B. Araújo, Jean Sévigny, Niels O. S. Câmara, Nils Ludwig, Elizandra Braganhol
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
tumor associated neutrophils
glioblastoma
tumor microenvironment
cancer
neutrophil extracellular traps
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1183465/full

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