Intervening in hnRNPA2B1-mediated exosomal transfer of tumor-suppressive miR-184-3p for tumor microenvironment regulation and cancer therapy

Intervening in hnRNPA2B1-mediated exosomal transfer of tumor-suppressive miR-184-3p for tumor microenvironment regulation and cancer therapy

Abstract Background Despite being a common malignant tumor, the molecular mechanism underlying the initiation and progression of triple-negative breast cancers (TNBCs) remain unclear. Tumor-associated macrophages (TAMs) are often polarized into a pro-tumor phenotype and are associated with a poor pr...

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Bibliographic Details
Main Authors: Xueqing Zhou, Yiling Hong, Yupeng Liu, Li Wang, Xuan Liu, Yi Li, Hong Yuan, Fuqiang Hu
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Nanobiotechnology
Subjects:
TNBCs
TAMs
Exosomes
miR-184-3p
hnRNPA2B1
Nanoparticle
Online Access:https://doi.org/10.1186/s12951-023-02190-w

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