Repetitively hypoxic preconditioning attenuates ischemia/reperfusion-induced liver dysfunction through upregulation of hypoxia-induced factor-1 alpha-dependent mitochondrial Bcl-xl in rat

Repetitively hypoxic preconditioning attenuates ischemia/reperfusion-induced liver dysfunction through upregulation of hypoxia-induced factor-1 alpha-dependent mitochondrial Bcl-xl in rat

Repetitive hypoxic preconditioning (HP) enforces protective effects to subsequently severe hypoxic/ischemic stress. We hypothesized that HP may provide protection against ischemia/reperfusion (I/R) injury in rat livers via hypoxia-induced factor-1 alpha (HIF-1α)/reactive oxygen species (ROS)-depende...

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Bibliographic Details
Main Authors: Pei-Lei Chou, Kuo-Hsin Chen, Tzu-Ching Chang, Chiang-Ting Chien
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Chinese Journal of Physiology
Subjects:
apoptosis
bcl-xl
hypoxia-inducible factor-1α
hypoxic preconditioning
reactive oxygen species
Online Access:http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2020;volume=63;issue=2;spage=68;epage=76;aulast=Chou

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