Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease presenting with recurrent inflammatory lesions in intertriginous body regions. HS has a pronounced impact on patients’ quality of life and is associated with a variety of comorbidities. Treatment of HS is often complex, requiring a...

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Main Authors: Lennart Ocker, Nessr Abu Rached, Caroline Seifert, Christina Scheel, Falk G. Bechara
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/23/7240
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author Lennart Ocker
Nessr Abu Rached
Caroline Seifert
Christina Scheel
Falk G. Bechara
author_facet Lennart Ocker
Nessr Abu Rached
Caroline Seifert
Christina Scheel
Falk G. Bechara
author_sort Lennart Ocker
collection DOAJ
description Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease presenting with recurrent inflammatory lesions in intertriginous body regions. HS has a pronounced impact on patients’ quality of life and is associated with a variety of comorbidities. Treatment of HS is often complex, requiring an individual approach with medical and surgical treatments available. However, especially in moderate-to-severe HS, there is an urgent need for new treatment approaches. In recent years, increased research has led to the identification of new potential therapeutic targets. This review aims to give a comprehensive and practical overview of current treatment options for HS. Furthermore, the clinically most advanced novel treatment approaches will be discussed.
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spelling doaj.art-952ba01d53ce48dcb3e985250c269b8d2023-11-24T11:25:21ZengMDPI AGJournal of Clinical Medicine2077-03832022-12-011123724010.3390/jcm11237240Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive ReviewLennart Ocker0Nessr Abu Rached1Caroline Seifert2Christina Scheel3Falk G. Bechara4International Centre for Hidradenitis Suppurativa/Acne Inversa (ICH), Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, 44791 Bochum, GermanyInternational Centre for Hidradenitis Suppurativa/Acne Inversa (ICH), Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, 44791 Bochum, GermanyInternational Centre for Hidradenitis Suppurativa/Acne Inversa (ICH), Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, 44791 Bochum, GermanyInternational Centre for Hidradenitis Suppurativa/Acne Inversa (ICH), Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, 44791 Bochum, GermanyInternational Centre for Hidradenitis Suppurativa/Acne Inversa (ICH), Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, 44791 Bochum, GermanyHidradenitis suppurativa (HS) is a chronic inflammatory skin disease presenting with recurrent inflammatory lesions in intertriginous body regions. HS has a pronounced impact on patients’ quality of life and is associated with a variety of comorbidities. Treatment of HS is often complex, requiring an individual approach with medical and surgical treatments available. However, especially in moderate-to-severe HS, there is an urgent need for new treatment approaches. In recent years, increased research has led to the identification of new potential therapeutic targets. This review aims to give a comprehensive and practical overview of current treatment options for HS. Furthermore, the clinically most advanced novel treatment approaches will be discussed.https://www.mdpi.com/2077-0383/11/23/7240hidradenitis suppurativaacne inversadermatologyinflammationtreatmentadalimumab
spellingShingle Lennart Ocker
Nessr Abu Rached
Caroline Seifert
Christina Scheel
Falk G. Bechara
Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review
Journal of Clinical Medicine
hidradenitis suppurativa
acne inversa
dermatology
inflammation
treatment
adalimumab
title Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review
title_full Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review
title_fullStr Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review
title_full_unstemmed Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review
title_short Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review
title_sort current medical and surgical treatment of hidradenitis suppurativa a comprehensive review
topic hidradenitis suppurativa
acne inversa
dermatology
inflammation
treatment
adalimumab
url https://www.mdpi.com/2077-0383/11/23/7240
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AT carolineseifert currentmedicalandsurgicaltreatmentofhidradenitissuppurativaacomprehensivereview
AT christinascheel currentmedicalandsurgicaltreatmentofhidradenitissuppurativaacomprehensivereview
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