Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFκB-mediated barrier protection.
The opportunistic fungal pathogen Candida albicans thrives on human mucosal surfaces as a harmless commensal, but frequently causes infections under certain predisposing conditions. Translocation across the intestinal barrier into the bloodstream by intestine-colonizing C. albicans cells serves as t...
Prif Awduron: | Jakob L Sprague, Tim B Schille, Stefanie Allert, Verena Trümper, Adrian Lier, Peter Großmann, Emily L Priest, Antzela Tsavou, Gianni Panagiotou, Julian R Naglik, Duncan Wilson, Sascha Schäuble, Lydia Kasper, Bernhard Hube |
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Fformat: | Erthygl |
Iaith: | English |
Cyhoeddwyd: |
Public Library of Science (PLoS)
2024-03-01
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Cyfres: | PLoS Pathogens |
Mynediad Ar-lein: | https://doi.org/10.1371/journal.ppat.1012031 |
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